{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:22:34Z","timestamp":1786990954044,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T00:00:00Z","timestamp":1624665600000},"content-version":"vor","delay-in-days":176,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pleomorphic adenoma of the minor salivary gland is not uncommon. Although malignant lesion is the most common in the minor salivary glands, benign lesion has been also reported. Many ectopic sites for minor salivary gland including the lip have been reported mainly intra-orally. But external cutaneous lesion is not that common, which will confuse the diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>This is a case report of a small 1.5 \u00d7 1 cm lesion in the left side of the upper lip in a healthy male. The lesion is fixed to the skin and was confused as dermal sebaceous cyst, which was excised with 2 mm safe margin under local anesthesia in an academic setting and closed primarily. Wound healed completely with no local complication and no evidence of recurrence in 1 year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Minor salivary glands are numerous in numbers specially in the oral cavity mainly in the hard and soft palate. Ectopic site in the head and neck area is well documented including the upper lip. But cutaneous presentation in the skin of the upper lip is not very common and can be easily missed especially if the specimen is not sent to permanent pathology. Pleomorphic adenoma has a unified histopathological feature that can be diagnosed by expert histopathologist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Even for benign looking skin lesions excision with safe margin and histopathology should be the standard of care. By executing this we ensure a serious malignancy will not be missed, were additional surgical or non-surgical management might be considered necessary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2021.106142","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T11:46:13Z","timestamp":1624967173000},"page":"106142","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["Rare upper lip pleomorphic adenoma presents as cutaneous skin lesion"],"prefix":"10.1097","volume":"85","author":[{"given":"Adnan G.","family":"Gelidan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Arab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-6-20260114","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s12663-010-0052-5","article-title":"Pleomorphic adenoma (benign mixed tumour) of the minor salivary glands of the upper lip","volume":"9","author":"Debnath","year":"2010","journal-title":"J. Maxillofac. Oral Surg"},{"key":"R3-6-20260114","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1600-0714.2007.00522.x","article-title":"Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from Northern California and comparison to reports from other parts of the world","volume":"36","author":"Buchner","year":"2007","journal-title":"J. Oral. Pathol. Med"},{"key":"R4-6-20260114","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s12070-018-1537-7","article-title":"Pleomorphic adenoma of upper lip: a rare case presentation","volume":"71","author":"Bhatia","year":"2019","journal-title":"Indian J. Otolaryngol. Head Neck Surg"},{"key":"R6-6-20260114","first-page":"352","article-title":"Pleomorphic adenoma of the upper lip : report of two cases","volume":"18","author":"Nagura","year":"2005","journal-title":"Jpn. J. Oral Diagn"},{"key":"R7-6-20260114","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3126\/jcmsn.v6i1.3603","article-title":"Pleomorphic adenoma of the upper lip: a case report","volume":"6","author":"Shrestha","year":"2010","journal-title":"J. Coll. Med. Sci. Nepal"},{"key":"R8-6-20260114","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus Surgical Case Report (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. Surg"},{"key":"R9-6-20260114","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2334\/josnusd.50.225","article-title":"Pleomorphic adenoma of the upper lip in a child","volume":"50","author":"Lotufo","year":"2008","journal-title":"J. Oral Sci"},{"key":"R10-6-20260114","doi-asserted-by":"crossref","first-page":"217","DOI":"10.4103\/0974-2077.91260","article-title":"Pleomorphic adenoma of the upper lip","volume":"4","author":"Kataria","year":"2011","journal-title":"J Cutan Aesthet Surg"},{"key":"R11-6-20260114","first-page":"59","article-title":"Pleomorphic adenoma in the upper lip: a case report and literature review","volume":"50","author":"Suka","year":"2021","journal-title":"J. Meikai Dent. Med"},{"key":"R12-6-20260114","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s12663-010-0052-5","article-title":"Pleomorphic adenoma (benign mixed tumour) of the minor salivary glands of the upperLip","volume":"9","author":"Debnath","year":"2010","journal-title":"J. Maxillofac. Oral Surg"},{"key":"R13-6-20260114","first-page":"e151","article-title":"Oral cancer associated with chronic mechanical irritation of the oral mucosa","volume":"23","author":"Piemonte","year":"2018","journal-title":"Med. Oral Patol. Oral Cir Bucal. Med. Oral S.L"},{"key":"R17-6-20260114","doi-asserted-by":"crossref","first-page":"33","DOI":"10.4103\/0019-5154.77548","article-title":"A Clinico-histopathological study of appendageal skin tumors, affecting head and neck region in patients attending the dermatology OPD of a tertiary care centre in eastern India","volume":"56","author":"Saha","year":"2011","journal-title":"Indian J. Dermatol"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221006441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221006441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.106142","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:19:25Z","timestamp":1768396765000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.106142"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":12,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2021.106142","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}