{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:44:06Z","timestamp":1780735446728,"version":"3.54.1"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,28]],"date-time":"2021-11-28T00:00:00Z","timestamp":1638057600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Thyroid cancer is the most common endocrine malignancy, while primary paraganglioma of the thyroid gland (TP) is an unusual tumour and in rare cases, this disease tends to mimic thyroid cancer. They are rare extra-adrenal neuroendocrine tumours originating from the neural crest, and are found almost exclusively in the head and neck area.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We present a case of a 53-year-old man, in whom a mediastinal lesion originating from the left lobe of the thyroid gland was found on routine ultrasound and subsequent computed tomography (CT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Total thyroidectomy and lymph dissection were performed. A review of the literature was made and a discussion was held regarding the diagnosis, the importance of surgical treatment and further behaviour.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Surgical removal of the thyroid gland is the main treatment, followed by radiation therapy. The diagnosis and differential diagnosis with other thyroid tumours is extremely important in terms of subsequent behaviour and prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2021.106649","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T12:16:31Z","timestamp":1638360991000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["A mediastinal malignant thyroid paraganglioma"],"prefix":"10.1097","volume":"90","author":[{"given":"Georgi","family":"Yankov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Ivanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marusya","family":"Genadieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Alexieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolay","family":"Yanev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desislava","family":"Ivanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-16-20260310","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s13244-012-0201-0","article-title":"A diagnostic approach to the mediastinal masses","volume":"4","author":"Juanpere","year":"2013","journal-title":"Insights Imaging"},{"key":"R3-16-20260310","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3945\/an.116.012211","article-title":"World Cancer Report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, WHO Press, 2015","volume":"7","author":"McGuire","year":"2016","journal-title":"Adv. Nutr"},{"key":"R5-16-20260310","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1089\/thy.2010.0332","article-title":"Prognostic factors and treatment outcomes of 100 cases of anaplastic thyroid carcinoma","volume":"21","author":"Akaishi","year":"2011","journal-title":"Thyroid"},{"key":"R6-16-20260310","first-page":"1","article-title":"Thyroid paraganglioma accompanied by lymph node metastasis or trachea invasion: a case report","volume":"20","author":"Yu","year":"2020","journal-title":"Oncol. 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Ital"},{"key":"R10-16-20260310","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1102\/1470-7330.2013.0013","article-title":"Imaging of thyroid carcinoma with CT and MRI: approaches to common scenarios","volume":"13","author":"Hoang","year":"2013","journal-title":"Cancer Imaging"},{"key":"R12-16-20260310","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12893-018-0354-y","article-title":"Diagnosis and management of a mediastinal ectopic thyroid laying on the right bronchus: case report and review of literature","volume":"18","author":"Metere","year":"2018","journal-title":"BMC Surg"},{"key":"R13-16-20260310","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1016\/j.ijsu.2015.12.048","article-title":"Surgical management of cervico-mediastinal goiters: our experience and review of the literature","volume":"28","author":"Crescenzo","year":"2016","journal-title":"Int. J. 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Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221011512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221011512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.106649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T10:00:51Z","timestamp":1773136851000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.106649"}},"subtitle":["A case report and literature review"],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":12,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2021.106649","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}