{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T22:26:54Z","timestamp":1781562414131,"version":"3.54.5"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Peripheral venous catheterizations in newborns are associated with complications such as infections, phlebitis, vessel rupture and drug leaks or serum. Extravasation injury refers to the leakage of injected drugs from blood vessels causing damage to the surrounding tissues, skin necrosis, and sometimes amputation. Using tilapia fish skin (TFS) is one of the new strategies that have been used in wound management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>This case is a 36-week- and 4-day-old male fetus with a birth weight of 1600 g, height of 40 cm, and head circumference of 31 cm who was born to a 25-year-old mother by cesarean section at Mahzad Obstetrics and Gynecology Hospital, Urmia, Iran. On the third day of hospitalization at neonatal intensive care unit (NICU), an extravasation injury occurred in the infant's left hand in size approximately 1 \u00d7 1 cm by peripheral catheter. Despite extensive intravenous antibiotic therapy and rinsing with normal saline, wound healing was not achieved. The necrotic area was bandaged by using of the tilapia skin. For this purpose, the area was first washed with normal saline for 5 min and then the tilapia skin was placed on the damaged skin for 10 days. After a month, the newborn's wound had completely healed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Infants are more prone to extravasation injury than adults due to being more sensitive and thinner peripheral vessel walls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case illustrates that tilapia fish skin may be a suitable alternative to other temporary skin cover dressings in premature newborns suffering from extravasation injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.106759","type":"journal-article","created":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T02:00:46Z","timestamp":1641866446000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Treatment of severe extravasation injury in a newborn by using tilapia fish skin"],"prefix":"10.1097","volume":"91","author":[{"given":"Navid","family":"Faraji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasoul","family":"Goli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoodreza","family":"Ghalandari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Taghavinia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behnam","family":"Malkari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Abbaszadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-17-20260304","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/s00737-018-0862-x","article-title":"A mindfulness intervention to reduce maternal distress in neonatal intensive care: a mixed methods pilot study","volume":"21","author":"Mendelson","year":"2018","journal-title":"Arch. Womens Ment. Health"},{"key":"R3-17-20260304","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3390\/ijerph15010060","article-title":"The neonatal intensive care unit: environmental stressors and supports","volume":"15","author":"Williams","year":"2018","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"R5-17-20260304","first-page":"52","article-title":"Incidence of infiltration\/extravasation in newborns using peripheral venous catheter and affecting factors","volume":"4","author":"Atay","year":"2018","journal-title":"Rev. Escola Enfermagem USP"},{"key":"R6-17-20260304","first-page":"224","article-title":"Efficacy of dehydrated human amniotic membrane allograft for the treatment of severe extravasation injuries in preterm neonates","volume":"30","author":"Boyar","year":"2018","journal-title":"Wounds"},{"key":"R9-17-20260304","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1093\/jbcr\/irz085","article-title":"Use of tilapia skin as a xenograft for pediatric burn treatment: a case report","volume":"40","author":"Costa","year":"2019","journal-title":"J. Burn Care Res"},{"key":"R10-17-20260304","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1097\/PRS.0000000000007895","article-title":"Nile tilapia fish skin-based wound dressing improves pain and treatment-related costs of superficial partial-thickness burns: a phase III randomized controlled trial","volume":"147","author":"Lima J\u00fanior","year":"2021","journal-title":"Plast. Reconstr. Surg"},{"key":"R11-17-20260304","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"1","author":"Agha","year":"2020","journal-title":"Int. J. Surg"},{"key":"R13-17-20260304","first-page":"2019","article-title":"Changing trend of neonatal septicemia and antibiotic susceptibility pattern of isolates in Nepal","volume":"6","author":"Thapa","year":"2019","journal-title":"Int. J. Pediatr"},{"key":"R14-17-20260304","doi-asserted-by":"crossref","first-page":"243","DOI":"10.5935\/2177-1235.2020RBCP0040","article-title":"Treatment of deep second-degree burns on the abdomen, thighs, and genitalia: use of tilapia skin as a xenograft","volume":"35","author":"Lima","year":"2001","journal-title":"Rev. Bras. Cir. Pl\u00e1st"},{"key":"R15-17-20260304","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/jbcr\/irz205","article-title":"Innovative burn treatment using tilapia skin as a xenograft: a phase ii randomized controlled trial","volume":"41","author":"Lima J\u00fanior","year":"2020","journal-title":"J. Burn Care Res"},{"key":"R16-17-20260304","first-page":"1955","article-title":"Use of Nile tilapia (Oreochromisniloticus) skin in the management of skin burns","volume":"67","author":"Osama","year":"2017","journal-title":"J. Pak. Med. Assoc"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222000050?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222000050?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.106759","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T10:03:19Z","timestamp":1772618599000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.106759"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":11,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.106759","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}