{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:44:05Z","timestamp":1774611845241,"version":"3.50.1"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T00:00:00Z","timestamp":1644883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Many studies have shown that COVID-19 can progress with coagulopathy and multisystemic thrombotic events. We report a patient who presented with abdominal pain after COVID-19 and was found to have splenic infarction (SI) concomitant with acute myocardial infarctus (MI) under anticoagulant treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 45-year-old man was admitted to the emergency department with left-sided abdominal pain radiating through to his back persisting for one day. He had COVID-19 PCR positivity nine days ago. After seven days of hospitalization due to COVID-19 pneumonia, he had been discharged with low-molecular-weight heparin (LMWH). Abdominal computerized tomography (CT) showed SI. His ECG and laboratory parameters were normal except for 17.2 \u00d7 10^3\/\u03bcL leukocytosis. The anticoagulant drug dose that he was taking was increased to 2 \u00d7 0.6 mL during hospitalization. He described new-onset chest pain during follow-up. Acute anterior MI was detected on ECG. Successful percutaneous coronary angiography was performed by cardiologists. No problems were observed in the follow-up. The patient was discharged on the fifth day of conservative treatment due to splenic infarction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Thrombosis prophylaxis with prophylactic doses of LMWH in hospitalized COVID-19 patients may not be sufficient to prevent the development of coagulopathy in patients. Abdominal-visceral thromboembolism should be suspected in a COVID-19-positive patient presenting with abdominal pain despite receiving anticoagulant therapy and normal d-dimer levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.106847","type":"journal-article","created":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T12:02:22Z","timestamp":1645185742000},"page":"106847","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Splenic infarct in a COVID-19 patient under anticoagulant therapy with normal D-dimer levels"],"prefix":"10.1097","volume":"92","author":[{"given":"Semra Demirli","family":"At\u0131c\u0131","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6ksever","family":"Akp\u0131nar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-37-20260310","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ijcard.2020.08.103","article-title":"A. Unusual arterial thrombotic events in Covid-19 patients","volume":"323","author":"de Roquetaillade","year":"2021","journal-title":"Int. J. Cardiol"},{"key":"R3-37-20260310","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. Surg"},{"key":"R4-37-20260310","first-page":"611","article-title":"Concomitant renal and splenic infarction as a complication of COVID-19: a case report and literature review","volume":"28","author":"Ramanathan","year":"2020","journal-title":"Infez. Med"},{"key":"R5-37-20260310","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ijscr.2020.09.078","article-title":"A case report of spontaneous hemoperitoneum in a COVID-19 patient","volume":"75","author":"Karki","year":"2020","journal-title":"Int. J. Surg. Case Rep"},{"key":"R7-37-20260310","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1111\/jth.14842","article-title":"Venous thromboembolism in COVID-19 patients","volume":"18","author":"Porfidia","year":"2020","journal-title":"J. Thromb. Haemost"},{"key":"R8-37-20260310","doi-asserted-by":"crossref","first-page":"455","DOI":"10.2147\/VHRM.S280962","article-title":"D-dimer, fibrinogen, and IL-6 in COVID-19 patients with suspected venous thromboembolism: a narrative review","volume":"16","author":"Eljilany","year":"2020","journal-title":"Vasc. Health Risk Manag"},{"key":"R9-37-20260310","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jacc.2020.05.053","article-title":"High prevalence of deep vein thrombosis in mechanically ventilated COVID-19 patients","volume":"76","author":"Voicu","year":"2020","journal-title":"J. Am. Coll. Cardiol"},{"key":"R10-37-20260310","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0140-6736(20)31182-X","article-title":"Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study","volume":"396","author":"COVIDSurg Collaborative","year":"2020","journal-title":"Lancet"},{"key":"R11-37-20260310","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1111\/jth.14854","article-title":"The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome","volume":"18","author":"Ranucci","year":"2020","journal-title":"J. Thromb. 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