{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T02:38:16Z","timestamp":1792463896844,"version":"4.5.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T00:00:00Z","timestamp":1649116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Klippel-Trenaunay Syndrome (KTS) is a rare congenital vascular disorder characterized by capillary malformation, varicosities, and tissue overgrowth. It usually affects the unilateral lower extremities manifesting commonly as pain, localized rise of temperature, and venous tortuosity. However, in severe cases, ulceration, cellulitis, and chronic lymphatic malformation may be present. Management is mostly supportive and involves the use of compression stockings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Here, we report a case of KTS with a persistent lateral marginal vein of Servelle managed with radiofrequency ablation along with sclerotherapy of selected perforators. On a two-year follow-up, the symptoms had resolved and Doppler ultrasonography revealed resolution of the defective vein along with the absence of incompetent perforators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>In cases with venous malformation with the persistence of embryonic avalvular venous structures, like the lateral marginal vein of Servelle, surgical intervention is warranted especially at a younger age to reduce the risk of future thromboembolic events and recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Varicosities of the lateral marginal vein of Servelle can be managed successfully by radiofrequency ablation and adjunct sclerotherapy in selected cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107052","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T19:33:08Z","timestamp":1649273588000},"page":"107052","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["A rare case of persistent lateral marginal vein of Servelle in Klippel Trenaunay Syndrome"],"prefix":"10.1097","volume":"94","author":[{"given":"S.","family":"Dahal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Karmacharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Vaidya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Gautam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Bhatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Bhandari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-58-20260304","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/0090-3019(94)90344-1","article-title":"The varicose osteohypertrophic nevus (klippel-trenaunay syndrome)","volume":"42","author":"Klippel","year":"1994","journal-title":"Surg. Neurol"},{"key":"R2-58-20260304","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1258\/026835507782655209","article-title":"Klippel-trenaunay syndrome: current management","volume":"22","author":"Gloviczki","year":"2007","journal-title":"Phlebology"},{"key":"R3-58-20260304","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/00000658-198503000-00020","article-title":"Klippel and Trenaunay's syndrome","volume":"201","author":"Servelle","year":"1985","journal-title":"Annals of Surgery"},{"key":"R4-58-20260304","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3400\/avd.oa.13-00111","article-title":"Endovenous radiofrequency thermal ablation and ultrasound-guided foam sclerotherapy in treatment of klippel-trenaunay syndrome","volume":"7","author":"Sermsathanasawadi","year":"2014","journal-title":"Ann. Vasc. Dis"},{"key":"R5-58-20260304","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE)Guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int J Surg"},{"key":"R6-58-20260304","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1067\/mva.2000.110343","article-title":"Surgical treatment of venous malformations in klippel-Tr\u00e9naunay syndrome","volume":"32","author":"Noel","year":"2000","journal-title":"J. Vasc. Surg"},{"key":"R7-58-20260304","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1177\/0268355515577322","article-title":"Surgical treatment of varicose veins and venous malformations in klippel-trenaunay syndrome","volume":"31","author":"Malgor","year":"2016","journal-title":"Phlebology"},{"key":"R9-58-20260304","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4103\/ijves.ijves_25_18","article-title":"Management of klippel-trenaunay syndrome from a single center in India: experience shared","volume":"5","author":"Stephen","year":"2018","journal-title":"Indian J. Vasc. Endovasc. Surg"},{"key":"R12-58-20260304","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4103\/ijves.ijves_25_18","article-title":"Management of klippel-trenaunay syndrome from a single center in India: experience shared","volume":"5","author":"Premkumar","year":"2018","journal-title":"Indian J. Vasc. Endovasc. Surg"},{"key":"R13-58-20260304","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/ijves.ijves_14_17","article-title":"Lateral marginal vein: have we understood its significance?","volume":"4","author":"Stephen","year":"2017","journal-title":"Indian J. Vasc. Endovasc. Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026122200298X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026122200298X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T10:07:41Z","timestamp":1772618861000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107052"}},"subtitle":["A successful surgical management"],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":10,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.107052","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}