{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T15:42:10Z","timestamp":1772638930818,"version":"3.50.1"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T00:00:00Z","timestamp":1649289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Negative pressure wound therapy (NPWT), also called vacuum-assisted closure, is an adjunctive therapy used to manage open wounds that apply subatmospheric pressure to the wound surface. The therapeutic effects of NPWT are exerted by stabilizing the wound environment, increasing blood flow, and macro-deformation of wounds that initiate granulation tissue formation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We present a case of a 28-year-old Caucasian male who developed a giant non-resolving hepatic abscess secondary to a gunshot wound (GSW) to the upper right abdomen. The abscess was successfully treated with open debridement followed by NWPT with instillation therapy. Significant reduction in abscess diameter and cessation of trauma-induced bile leak was observed following 15 days of wound vac treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Wound vac treatment was essential in this patient due to the inherent erosive properties of bile that damage surrounding tissue and perpetuate opportunistic growth of pathogenic microbes. Prior to standard NPWT treatment, debridement of devitalized tissues and infection should be managed; however, instillation therapy has permitted NPWT to be used in the presence of infection or as an adjuvant to surgical infection management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>NPWT is indicated for a wide range of acute and chronic wounds; however, the utilization of NPWT to treat abscesses remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107068","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T02:13:07Z","timestamp":1649643187000},"page":"107068","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Negative pressure wound therapy with intermittent irrigation for treatment of post-traumatic giant abscess"],"prefix":"10.1097","volume":"94","author":[{"given":"Mohammad","family":"Abidali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Gottlieb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Abidali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-71-20260304","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/iwj.12171","article-title":"Science supporting negative pressure wound therapy with instillation","volume":"10","author":"Rycerz","year":"2013","journal-title":"Int. Wound J"},{"key":"R2-71-20260304","doi-asserted-by":"crossref","first-page":"658","DOI":"10.5152\/tjg.2018.18373","article-title":"Vacuum-assisted closure in the treatment of biliary leakage following gunshot injury to the liver","volume":"30","author":"Simsek","year":"2019","journal-title":"Turk. J. Gastroenterol"},{"key":"R4-71-20260304","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/hpb.12445","article-title":"Video-assisted hepatic abscess debridement","volume":"17","author":"Klink","year":"2015","journal-title":"HPB (Oxford"},{"key":"R7-71-20260304","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ijscr.2020.04.092","article-title":"Acute liver abscess after non-operative management of blunt liver injury: a rare case managed with laparoscopic drainage","volume":"71","author":"Lin","year":"2020","journal-title":"Int. J. Surg. Case Rep"},{"key":"R8-71-20260304","doi-asserted-by":"crossref","first-page":"103","DOI":"10.14701\/kjhbps.2015.19.3.103","article-title":"Comparison between operative versus non-operative management of traumatic liver injury","volume":"19","author":"Park","year":"2015","journal-title":"Korean J. Hepato-Biliary-Pancreatic Surg"},{"key":"R9-71-20260304","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1038\/s41374-020-00478-1","article-title":"Pseudomonas aeruginosa virulence proteins pseudolysin and protease IV impede cutaneous wound healing","volume":"100","author":"Prasad","year":"2020","journal-title":"Lab. Investig"},{"key":"R10-71-20260304","first-page":"1","article-title":"Negative-pressure wound therapy in a Pseudomonas aeruginosa infection model","volume":"2018","author":"Wang","year":"2018","journal-title":"Biomed. Res. Int"},{"key":"R11-71-20260304","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.21873\/invivo.11636","article-title":"Impact of bile exposure time on Organ\/space surgical site infections after pancreaticoduodenectomy","volume":"33","author":"Kumagai","year":"2019","journal-title":"In Vivo"},{"key":"R12-71-20260304","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/eye.1998.175","article-title":"Effect of bile acids on fibroblast proliferation and viability","volume":"12","author":"Ramaesh","year":"1998","journal-title":"Eye"},{"key":"R13-71-20260304","first-page":"327","article-title":"Nutrition in wound care management: a comprehensive overview","volume":"27","author":"Quain","year":"2015","journal-title":"Wounds"},{"key":"R14-71-20260304","doi-asserted-by":"crossref","first-page":"1e","DOI":"10.1097\/01.prs.0000222562.60260.f9","article-title":"Wound healing: an overview","volume":"117","author":"Broughton","year":"2006","journal-title":"Plast. Reconstr. Surg"},{"key":"R15-71-20260304","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.12968\/bjon.2011.20.Sup6.S4","article-title":"Effect of nutrition on wound healing in older people: a case study","volume":"20","author":"Timms","year":"2011","journal-title":"Br. J. Nurs"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222003145?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222003145?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T10:00:49Z","timestamp":1772618449000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107068"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":12,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.107068","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}