{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:55:12Z","timestamp":1792133712619,"version":"4.4.0"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>\n                      Calcific myonecrosis (CM) is a rare, benign post-traumatic sequela which is often challenging to differentiate from soft tissue tumors. Infected CM is recalcitrant and sometimes requires invasive treatment despite its benign nature. We present a case of infected CM in which MRI and\n                      <jats:sup>201<\/jats:sup>\n                      Tl scintigraphy proved useful for diagnosis and intralesional debridement with prolonged placement of a suction tube allowed for successful treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>\n                      A 71-year-old man had undergone repeated aspiration for swelling of the lower leg and presented with a sustained pyogenic discharging wound. He underwent intralesional debridement of purulent necrotic tissue followed by prolonged suction tube placement.\n                      <jats:italic toggle=\"yes\">Enterobacter cloacae<\/jats:italic>\n                      was detected in the discharge, and specific antibiotics were administered. Once the wound closed, a new sinus recurred four months after surgery, warranting reoperation with debridement of the remnant fascia and necrotic tissue with suction tube replacement. The wound healed eight months after the first surgery with no signs of recurrence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>CM can be diagnosed based on its unique imaging features and a history of compartment syndrome. To avoid infection, CM must be treated conservatively without surgical invasions, such as biopsy or aspiration. Extensive debridement with a myocutaneous flap is nevertheless recommended for infected CM treatment, despite significant invasion including intraoperative bleeding being problematic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      MRI and\n                      <jats:sup>201<\/jats:sup>\n                      Tl scintigraphy can help diagnose CM and avoid biopsy to exclude malignancy. Intralesional debridement of necrotic tissue with prolonged suction tube placement could be a valid treatment alternative to reduce the invasiveness of infected CM.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107145","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T04:30:53Z","timestamp":1651811453000},"page":"107145","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Treatment of infected calcific myonecrosis with chronically discharging sinus caused by iatrogenic aspiration"],"prefix":"10.1097","volume":"95","author":[{"given":"Takashi","family":"Higuchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norio","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideji","family":"Nishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20260304","first-page":"7909","article-title":"Calcific myonecrosis mimicking soft tissue sarcoma: a case report","volume":"15","author":"Ukon","year":"2018","journal-title":"Oncol. 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Radiol"},{"key":"R5-14-20260304","doi-asserted-by":"crossref","first-page":"e158","DOI":"10.1308\/rcsann.2018.0077","article-title":"Calcific myonecrosis: diagnostic dilemma","volume":"100","author":"Matar","year":"2018","journal-title":"Ann. R. Coll. Surg. Engl"},{"key":"R7-14-20260304","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/iwj.12833","article-title":"A challenging case of calcific myonecrosis of tibialis anterior and hallucis longus muscles with a chronic discharging wound","volume":"15","author":"Tan","year":"2018","journal-title":"Int. Wound J"},{"key":"R8-14-20260304","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1097\/00005373-199510000-00037","article-title":"Calcific myonecrosis following compartment syndrome: report of two cases, review of the literature, and recommendations for treatment","volume":"39","author":"Snyder","year":"1995","journal-title":"J. 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A late sequela to compartment syndrome of the leg","volume":"13","author":"O'Keefe","year":"1995","journal-title":"Clin. Orthop. Relat. Res"},{"key":"R13-14-20260304","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1080\/03009730903016050","article-title":"Calcific myonecrosis and the role of imaging in the diagnosis: a case report","volume":"114","author":"Okada","year":"2009","journal-title":"Ups. J. Med. Sci"},{"key":"R14-14-20260304","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s11604-012-0077-4","article-title":"Calcific myonecrosis: a two-patient case series","volume":"30","author":"De Carvalho","year":"2012","journal-title":"Jpn. J. Radiol"},{"key":"R15-14-20260304","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1186\/1752-1947-8-193","article-title":"Calcific myonecrosis following snake bite: a case report and review of the literature","volume":"8","author":"Yuenyongviwat","year":"2014","journal-title":"J. Med. 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