{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:10:22Z","timestamp":1773054622559,"version":"3.50.1"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:00:00Z","timestamp":1654646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Mucormycosis is an opportunistic mycosis common in poorly-controlled insulin dependent diabetic patients particularly with ketoacidosis. Fungal osteomyelitis is a life-threatening condition affectation of the nose and paranasal sinuses within the orofacial region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>We present a 63-year-old diabetic male patient with maxillary mucormycotic osteomyelitis threatening his better seeing eye and review the clinical symptoms, relevant imaging, and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>We highlight a rare pattern of craniofacial fungal bone infection with maxillary and orbital involvement that ultimately spared the optic nerve. This case report offers the clinician a review of important clinical and diagnostic findings that can help direct the need for orbital exenteration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Maxillary mucormycotic osteomyelitis is an aggressive infection that needs to be addressed promptly to prevent fatal consequences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107299","type":"journal-article","created":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T11:40:10Z","timestamp":1655120410000},"page":"107299","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Extent of craniofacial fungal osteomyelitis in a ketoacidotic patient may predict optic nerve involvement"],"prefix":"10.1097","volume":"96","author":[{"given":"Jennifer","family":"Adams","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid N.","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Bender-Heine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R2-27-20260309","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s12663-011-0283-0","article-title":"Osteomyelitis of maxilla in poorly controlled diabetics in a rural Indian population","volume":"11","author":"Peravali","year":"2012","journal-title":"J. Maxillofac. Oral Surg"},{"key":"R3-27-20260309","first-page":"57","article-title":"Osteomyelitis of maxilla bilateral involvement: a case report","volume":"2","author":"Manimaran","year":"2011","journal-title":"JIADS"},{"key":"R4-27-20260309","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1007\/s00405-005-0919-0","article-title":"Rhinocerebral mucormycosis: pathways of spread","volume":"262","author":"Hosseini","year":"2005","journal-title":"Eur. Arch. Otorhinolaryngol"},{"key":"R5-27-20260309","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1086\/432579","article-title":"Epidemiology and outcome of zygomycosis: a review of 929 reported cases","volume":"41","author":"Roden","year":"2005","journal-title":"Clin. Infect. Dis"},{"key":"R6-27-20260309","first-page":"e107","article-title":"Invasive rhinocerebral mucormycosis with orbital extension in poorly controlled diabetes","volume":"50","author":"Hadzri","year":"2009","journal-title":"Singap. Med. J"},{"key":"R7-27-20260309","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"International Journal of Surgery"},{"key":"R8-27-20260309","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.3390\/diagnostics11112050","article-title":"Maxillary mucormycosis osteomyelitis in post COVID-19 patients: a series of fourteen cases","volume":"11","author":"Said Ahmed","year":"2021","journal-title":"Diagnostics (Basel"},{"key":"R9-27-20260309","doi-asserted-by":"crossref","first-page":"748","DOI":"10.4103\/jfmpc.jfmpc_410_18","article-title":"Mucormycotic osteomyelitis of maxilla following maxillofacial trauma: the disease of the diseased","volume":"8","author":"Srivastava","year":"2019","journal-title":"J. Family Med. Prim. Care"},{"key":"R10-27-20260309","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.4103\/ijo.IJO_1165_21","article-title":"Rhino-orbito-cerebral mucormycosis-guidelines for diagnosis, staging and management","volume":"69","author":"Honavar","year":"2021","journal-title":"Indian J. Ophthalmol"},{"key":"R11-27-20260309","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s12070-018-1293-8","article-title":"Orbital exenteration in rhino-orbito-cerebral mucormycosis: a prospective analytical study with scoring system","volume":"71","author":"Shah","year":"2019","journal-title":"Indian J. Otolaryngol. Head Neck Surg"},{"key":"R12-27-20260309","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00238-019-01606-x","article-title":"Cranio-facial mucormycosis\u2014the plastic surgeon's perspective","volume":"43","author":"Srikanth","year":"2020","journal-title":"Eur. J. Plast. Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222005454?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222005454?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107299","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:08:34Z","timestamp":1773047314000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107299"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":11,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.107299","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}