{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:30:46Z","timestamp":1777725046287,"version":"3.51.4"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T00:00:00Z","timestamp":1658102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Granulomatosis with polyangiitis is a rare vasculitis. The gastrointestinal symptoms and complications of the disease are rare in GPA patients. One the rarest is intestinal obstruction which when found was always caused by bowel perforation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Here we report the case of a 14 years-old female patient who is a known case of granulomatosis with polyangiitis presented with intestinal obstruction without perforation and treated conservatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Gastrointestinal involvement is seen in only 5\u201310 % of the cases and is a poor prognostic factor. This life-threatening complication could be caused by bowel perforation and as we describe here with bowel inflammation only without perforation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Intestinal obstruction without perforations is a new complication of GPA. And conservative management should be considered in the plan of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107446","type":"journal-article","created":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T13:01:50Z","timestamp":1658408510000},"page":"107446","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Granulomatosis with polyangiitis presenting with intestinal obstruction"],"prefix":"10.1097","volume":"97","author":[{"given":"Reem","family":"Alawna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tala","family":"Jalamneh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maram","family":"Massad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noor","family":"Alawna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdalaziz","family":"Rabaia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadi Abu","family":"Alrub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-74-20260309","doi-asserted-by":"crossref","first-page":"415","DOI":"10.4103\/ijn.IJN_141_18","article-title":"Gastrointestinal involvement in granulomatosis with polyangiitis: case report and review","volume":"29","author":"Ramachandran","year":"2019","journal-title":"Indian J.Nephrol"},{"key":"R2-74-20260309","first-page":"151","article-title":"Wegener's granulomatosis. Anatomic correlates, a proposed classification. Mayo Clinic Proceedings 51(12), 777-781. As referenced in Greco, A., Marinelli, C., Fusconi, M., Macri, G., Gallo, A., de Virgilio, A., Zambetti, G., & de Vincentiis, M. (2015). Clinic manifestations in granulomatosis with polyangiitis","volume":"29","author":"De Remee","year":"1976","journal-title":"Int. J. Immunopathol. Pharmacol"},{"key":"R3-74-20260309","doi-asserted-by":"crossref","first-page":"270","DOI":"10.5114\/pg.2016.57887","article-title":"Gastrointestinal tract involvement in granulomatosis with polyangiitis","volume":"4","author":"Masiak","year":"2016","journal-title":"Gastroenterol.Rev"},{"key":"R4-74-20260309","first-page":"151","article-title":"Wegener's granulomatosis presenting as a recurrence of chronic otitis media. American Journal of Otolaryngology, 19(1), 54-60. doi:10.1016\/s0196-0709(98)90067-9. As referenced in Greco, A., Marinelli, C., Fusconi, M., Macri, G., Gallo, A., de Virgilio, A., Zambetti, G., & de Vincentiis, M. (2015). Clinic manifestations in granulomatosis with polyangiitis","volume":"29","author":"Hartl","year":"1998","journal-title":"Int. J. Immunopathol. Pharmacol"},{"key":"R5-74-20260309","first-page":"151","article-title":"Otological manifestations of Wegener's granulomatosis. Indian Journal of Otology 4: 29-36. As referenced in Greco, A., Marinelli, C., Fusconi, M., Macri, G., Gallo, A., de Virgilio, A., Zambetti, G., & de Vincentiis, M. (2015). Clinic manifestations in granulomat","volume":"29","author":"Wali","year":"1998","journal-title":"Int. J. Immunopathol. Pharmacol"},{"key":"R6-74-20260309","first-page":"151","article-title":"Otological Wegeners Granulomatosis: a diagnostic dilemma. Clinical Otolaryngology and Allied Sciences, 25(6), 433-434. doi:10.1046\/j.1365-2273.2000.00335.x. As referenced in Greco, A., Marinelli, C., Fusconi, M., Macri, G., Gallo, A., de Virgilio, A., Zambetti, G., & de Vincentiis, M. (2015). Clinic manifestations in granulomatosis with polyangiitis","volume":"29","author":"Thornton","year":"2000","journal-title":"Int. J. Immunopathol. Pharmacol"},{"key":"R7-74-20260309","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1177\/0394632015617063","article-title":"Clinic manifestations in granulomatosis with polyangiitis","volume":"29","author":"Greco","year":"2015","journal-title":"Int. J. Immunopathol. Pharmacol"},{"key":"R8-74-20260309","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222006927?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222006927?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:04:23Z","timestamp":1773047063000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107446"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":8,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.107446","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]}}}