{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T23:31:41Z","timestamp":1775863901076,"version":"3.50.1"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T00:00:00Z","timestamp":1665100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Acute appendicitis associated with ovarian epidermoid cyst torsion is extremely rare. To our knowledge, there are about 7 cases that have been reported in English literature, and there was no epidermoid cyst in any of them.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Herein, we present the case of a 2.5-year-old girl with a history of vomiting, fever, and abdominal pain. She was prepared for the operation following the clinical and radiological assessment. At laparotomy, appendicitis and left ovarian lesion torsion were found. An appendectomy and salpingo-oophorectomy were performed with no complications occurring during surgery or the follow-up period. The results of the histology analysis showed that the appendix was inflamed and that there was an epidermoid cyst with a wide infarction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Epidermoid cysts of the ovary are uncommon and often discovered by accident, and histological investigation is required for a definitive diagnosis. In our case, the signs and symptoms before surgery suggested appendicitis. Acute appendicitis in young children is also uncommon. Ovarian lesion torsion associated with acute appendicitis is extremely rare. The treatment is surgery and often requires appendectomy and salpingo-oopherectomy as in our case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Such cases should be considered in the differential diagnosis of abdominal pain at any age, and early diagnosis and surgery are always required.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107731","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T04:41:15Z","timestamp":1665463275000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Synchronous ovarian epidermoid cyst torsion with appendicitis in a 2.5-year-old girl"],"prefix":"10.1097","volume":"100","author":[{"given":"Gulan","family":"Maree","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferhad","family":"Hemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaa","family":"Ghuzlan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Kassab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rana","family":"Issa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ammar","family":"Omran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-18-20260313","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s00383-002-0775-6","article-title":"Appendicitis in children less than 3 years of age: a 28-year review","volume":"19","author":"Alloo","year":"2004","journal-title":"Pediatr. Surg. Int"},{"key":"R2-18-20260313","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13052-017-0335-2","article-title":"Acute appendicitis in young children less than 5 years: review article","volume":"43","author":"Almaramhy","year":"2017","journal-title":"Ital. J. Pediatr"},{"key":"R4-18-20260313","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1016\/j.jpedsurg.2005.05.068","article-title":"Ovarian torsion associated with appendicitis in a 5-year-old girl: a case report and review of the literature","volume":"40","author":"Hoey","year":"2005","journal-title":"J. Pediatr. Surg"},{"key":"R5-18-20260313","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. Surg"},{"key":"R6-18-20260313","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.suc.2016.08.008","article-title":"Pediatric ovarian torsion","volume":"97","author":"Childress","year":"2017","journal-title":"Surg. Clin. North Am"},{"key":"R7-18-20260313","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1503\/cjs.013311","article-title":"Pediatric ovarian torsion: case series and review of the literature","volume":"56","author":"Poonai","year":"2013","journal-title":"Can. J. Surg"},{"key":"R8-18-20260313","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1590\/S1676-24442013000200009","article-title":"Intratesticular and intraovarian epidermoid inclusion cysts: report of two cases","volume":"49","author":"Morgan","year":"2013","journal-title":"Jornal Brasileiro de Patologia e Medicina Laboratorial"},{"key":"R9-18-20260313","first-page":"263","article-title":"Epidermoid cyst of the ovary","volume":"57","author":"Idress","year":"2007","journal-title":"J. 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