{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T23:33:21Z","timestamp":1773963201884,"version":"3.50.1"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Leiomyosarcoma (LMS) is a malignant tumor of the uterine smooth muscle. It is highly aggressive and accounts for 1 % of all uterine malignancies. Symptoms often include a rapidly growing mass, with an average course of illness ranging from six to eight months. Leiomyosarcomas are rare in younger individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 31-year-old nulliparous woman was diagnosed with a suspected malignant ovarian tumor. A unilateral salpingo-oophorectomy and surgical staging were planned to preserve the patient's fertility. However, the large solid mass was found to be arising from the uterus during surgery. In light of the preference for fertility preservation, a myomectomy was performed, with subsequent pathology results showing a malignant leiomyosarcoma. Following counseling and discussion with the patient and her spouse, follow-up surgery was performed to ensure a free surgical margin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Leiomyosarcomas at a young age is very rare, and early diagnosis is quite a challenge, especially when the tumor characteristics are not atypical. Thus, surgical evaluation and staging are paramount.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Surgical diagnosis of any mass with a history of rapid enlargement and characteristics of malignancy is very important, especially when anatomical landmarks are distorted due to the enlarged mass.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107758","type":"journal-article","created":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T01:16:39Z","timestamp":1666574199000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Occult leiomyosarcoma simulating malignant ovarian tumor"],"prefix":"10.1097","volume":"100","author":[{"given":"Herlangga","family":"Pramaditya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brahmana Askandar","family":"Tjokroprawiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-43-20260313","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1634\/theoncologist.2014-0361","article-title":"Age-stratified risk of unexpected uterine sarcoma following surgery for presumed benign leiomyoma","volume":"20","author":"Brohl","year":"2015","journal-title":"The Oncologist [Internet"},{"key":"R2-43-20260313","doi-asserted-by":"crossref","first-page":"735","DOI":"10.3390\/diagnostics10100735","article-title":"Developing a preoperative algorithm for the diagnosis of uterine leiomyosarcoma","volume":"10","author":"Lawlor","year":"2020","journal-title":"Diagnostics [Internet"},{"key":"R3-43-20260313","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1055\/s-0041-1730098","article-title":"Leiomyosarcoma of uterus in a nulliparous female: mimicking as ovarian malignancy","volume":"07","author":"Mishra","year":"2021","journal-title":"Asian Journal of Oncology [Internet"},{"key":"R4-43-20260313","first-page":"1","article-title":"A rare case report of uterine leiomyosarcoma in young age","volume":"18","author":"Jayasri","year":"2019","journal-title":"IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) [Internet"},{"key":"R5-43-20260313","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"International Journal of Surgery [Internet"},{"key":"R6-43-20260313","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.gynor.2014.05.004","article-title":"Uterine sarcoma in a 14year-old girl presenting with uterine rupture","volume":"10","author":"\u00d6zcan","year":"2014","journal-title":"Gynecologic Oncology Reports [Internet"},{"key":"R7-43-20260313","doi-asserted-by":"crossref","first-page":"546","DOI":"10.5603\/GP.a2018.0093","article-title":"Occult uterine leiomyosarcoma in women undergoing abdominal and minimally invasive surgeries for myomas","volume":"89","author":"Ludwin","year":"2018","journal-title":"Ginekologia Polska [Internet"},{"key":"R8-43-20260313","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4103\/GMIT.GMIT_10_18","article-title":"Outcome and management of uterine leiomyosarcoma treated following surgery for presumed benign disease: review of literature","volume":"7","author":"Tantitamit","year":"2018","journal-title":"Gynecology and Minimally Invasive Therapy [Internet"},{"key":"R9-43-20260313","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.2214\/AJR.17.19234","article-title":"Uterine leiomyosarcoma: can MRI differentiate leiomyosarcoma from benign leiomyoma before Treatment?","volume":"211","author":"DeMulder","year":"2018","journal-title":"American Journal of Roentgenology [Internet"},{"key":"R10-43-20260313","doi-asserted-by":"crossref","first-page":"775","DOI":"10.15562\/bmj.v10i2.2395","article-title":"Unexpected leiomyosarcoma after total abdominal hysterectomy with indication uterine myoma in nullipara: a case report","volume":"10","author":"Yeni","year":"2021","journal-title":"Bali Medical Journal [Internet"},{"key":"R11-43-20260313","doi-asserted-by":"crossref","first-page":"189","DOI":"10.31689\/rmm.2019.26.4.189","article-title":"KLK6 as a predictor of ovarian malignancy","volume":"26","author":"Perbowo","year":"2019","journal-title":"Medicina Moderna - Modern Medicine [Internet"},{"key":"R13-43-20260313","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1200\/JCO.2017.75.9845","article-title":"Soft tissue and uterine leiomyosarcoma","volume":"36","author":"George","year":"2018","journal-title":"Journal of Clinical Oncology [Internet"},{"key":"R14-43-20260313","doi-asserted-by":"crossref","first-page":"3192","DOI":"10.53730\/ijhs.v6nS6.11295","article-title":"Psychosocial perspective of patients with gynecological cancer towards medical services during the coronavirus disease pandemic at RSUD Dr. Soetomo, Surabaya, Indonesia","volume":"30","author":"Pratiktio","year":"2022","journal-title":"International journal of health sciences [Internet"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222010045?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222010045?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T11:03:10Z","timestamp":1773399790000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107758"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":13,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.107758","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]}}}