{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:31:35Z","timestamp":1787895095099,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Primary chylopericardium is an extremely rare disease with no previous reported case in Indonesia. It may be caused by an abnormality of lymphatic drainage in the thoracic region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We report the case of a 19-year-old female who presented with a chief complaint of shortness of breath and fluid accumulation in her pericardial sac. Screening for autoimmune disease, tuberculosis, and malignancy all came back negative. Lymphoscintigraphy showed suspected leakage or obstruction of lymph at the supradiaphragmatic level. The patient was diagnosed with primary chylopericardium. In a span of 1 year, she had undergone 3 pericardiocentesis procedures and declined surgical treatment. On her fourth pericardiocentesis, the cardiologists were unable to remove fluid from the pericardial sac. Thoracic duct ligation and pericardial window were eventually performed and a total of 850 ml of chylous fluid was removed. At 6 months postoperation patient showed no signs and symptoms of pericardial effusion and was in good condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Constrictive pericarditis can occur as a complication of chronic inflammation in the pericardium due to the presence of chylopericardium and a history of multiple pericardiocenteses. However, there are no reports regarding the exact duration of chylopericardium that will lead to constrictive pericarditis. Difficulty in pericardiocentesis might be an early sign of scarring in the pericardium.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Delayed surgical treatment of chylopericardium increases the risk of constrictive pericarditis and significantly reduces the patient's quality of life due to recurrent symptoms and hospitalizations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107764","type":"journal-article","created":{"date-parts":[[2022,10,22]],"date-time":"2022-10-22T12:21:17Z","timestamp":1666441277000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Isolated primary chylopericardium"],"prefix":"10.1097","volume":"100","author":[{"given":"Muhammad Arza","family":"Putra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Grantomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Melisa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-47-20260313","first-page":"249","article-title":"Idiopathic chylopericardium","volume":"33","author":"Mehrotra","year":"2006","journal-title":"Tex. Heart Inst. J"},{"key":"R3-47-20260313","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. Surg"},{"key":"R4-47-20260313","first-page":"419","article-title":"Primary chylopericardium: a case report and literature review","volume":"15","author":"Yu","year":"2018","journal-title":"Exp Ther Med"},{"key":"R5-47-20260313","first-page":"e173","article-title":"Primary chylopericardium","volume":"5","author":"Kawano","year":"2012","journal-title":"J. Cardiol. Cases"},{"key":"R6-47-20260313","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jtcvs.2008.03.033","article-title":"Chylopericardium in adults: a literature review over the past decade (1996-2006)","volume":"136","author":"Dib","year":"2008","journal-title":"J. Thorac. Cardiovasc. Surg"},{"key":"R8-47-20260313","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/0016-5085(89)90650-1","article-title":"Dietary modification of chyle composition in chylothorax","volume":"97","author":"Jensen","year":"1989","journal-title":"Gastroenterology"},{"key":"R9-47-20260313","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1016\/S0003-4975(00)01921-4","article-title":"Thoracoscopic direct clipping of the thoracic duct for chylopericardium and chylothorax","volume":"70","author":"Wurnig","year":"2000","journal-title":"Ann. Thorac. Surg"},{"key":"R10-47-20260313","doi-asserted-by":"crossref","first-page":"3","DOI":"10.21037\/med-20-64","article-title":"Review of chylopericardium","volume":"6","author":"Rochefort","year":"2022","journal-title":"Mediastinum"},{"key":"R12-47-20260313","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0002-8703(85)90614-3","article-title":"Constrictive pericarditis secondary to primary chylopericardium","volume":"109","author":"Morishita","year":"1985","journal-title":"Am. Heart J"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222010100?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261222010100?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107764","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T11:03:03Z","timestamp":1773399783000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107764"}},"subtitle":["A rare case report and literature review"],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":9,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.107764","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]}}}