{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T15:01:41Z","timestamp":1773414101764,"version":"3.50.1"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>ABSTRACT<\/jats:title>\n                    <jats:p>Endodermal Sinus tumor is a rare malignant type of germ cell tumor (GCT). Primary endodermal sinus tumor, especially in the head of pancreas, is extremely rare. The case under consideration is of a 22 year old male who presented with pancreatic mass causing postprandial nausea and vomiting, and raised AFP levels. The biopsy of the mass revealed the endodermal sinus tumor, and the pancreatic origin was confirmed by a CT scan and a negative scrotal ultrasound. As the tumor was unresectable initially, a gastrojejunostomy was done to relieve the obstructive symptoms. Whipple procedure was performed two months after 4 cycles of BEP chemotherapy to remove the residual tumor in pancreas. It is crucial to highlight this uncommon case in order to increase surgeons' and oncologists' knowledge of the malignant extra-gonadal GCTs diagnosis and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107783","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T02:44:19Z","timestamp":1668739459000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Endodermal sinus tumor with pancreatic origin"],"prefix":"10.1097","volume":"101","author":[{"given":"Muhammad Jawad","family":"Zahid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Musarrat","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Zeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul","family":"Haseeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hira Bakhtiyar","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-12-20260313","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijsu.2018.10.028","article-title":"The SCARE 2018 statement: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"60","author":"Agha","year":"2018","journal-title":"Int. J. Surg"},{"key":"R3-12-20260313","doi-asserted-by":"crossref","first-page":"5982","DOI":"10.3390\/ijms22115982","article-title":"To be or not to be a germ cell: the extragonadal germ cell tumor paradigm","volume":"22","author":"De Felici","year":"2021","journal-title":"Int. J. Mol. Sci"},{"key":"R4-12-20260313","doi-asserted-by":"crossref","first-page":"472","DOI":"10.3348\/kjr.2010.11.4.472","article-title":"Primary yolk sac tumor arising in the pancreas with hepatic metastasis: a case report","volume":"11","author":"Zhang","year":"2010","journal-title":"Korean J. Radiol"},{"key":"R6-12-20260313","doi-asserted-by":"crossref","first-page":"475","DOI":"10.2350\/11-01-0975-CR.1","article-title":"Yolk sac tumor of the thyroid gland: a case report","volume":"14","author":"Furtado","year":"2011","journal-title":"Pediatr. Dev. Pathol"},{"key":"R8-12-20260313","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1016\/j.jpedsurg.2012.10.054","article-title":"Primary mixed germ cell tumor arising in the pancreatic head","volume":"48","author":"Wang","year":"2013","journal-title":"J. Pediatr. Surg"},{"key":"R9-12-20260313","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.pan.2019.12.021","article-title":"A yolk sac tumor of the pancreas and derived xenograft model effectively responded to VIP chemotherapy","volume":"20","author":"Yonemaru","year":"2020","journal-title":"Pancreatology"},{"key":"R10-12-20260313","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1443-1661.2011.01142.x","article-title":"Histological diagnosis by EUS-guided fine-needle aspiration biopsy in pancreatic solid masses without on-site cytopathologist: a single-center experience","volume":"23","author":"Itoi","year":"2011","journal-title":"Dig. Endosc"},{"key":"R11-12-20260313","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/RLU.0000000000003038","article-title":"Primary pancreatic yolk sac tumor presenting as diffusely enlarged pancreas in initial 18F-FDG PET\/CT","volume":"45","author":"Sui","year":"2020","journal-title":"Clin. Nucl. Med"},{"key":"R13-12-20260313","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.pan.2019.12.021","article-title":"A yolk sac tumor of the pancreas and derived xenograft model effectively responded to VIP chemotherapy","volume":"20","author":"Yonemaru","year":"2020","journal-title":"Pancreatology"},{"key":"R14-12-20260313","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1053\/jpsu.2001.19993","article-title":"The effect of cisplatin dose and surgical resection in children with malignant germ cell tumors at the sacrococcygeal region: a pediatric intergroup trial (POG 9049\/CCG 8882)","volume":"36","author":"Rescorla","year":"2001","journal-title":"J. Pediatr. Surg"},{"key":"R15-12-20260313","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1053\/jpsu.2001.19995","article-title":"Malignant mediastinal germ cell tumors: an intergroup study","volume":"36","author":"Billmire","year":"2001","journal-title":"J. Pediatr. Surg"},{"key":"R16-12-20260313","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1200\/JCO.2004.08.015","article-title":"Randomized comparison of combination chemotherapy with etoposide, bleomycin, and either high-dose or standard-dose cisplatin in children and adolescents with high-risk malignant germ cell tumors: a pediatric intergroup study-Pediatric oncology group 9049 and Children's cancer group 8882","volume":"22","author":"Cushing","year":"2004","journal-title":"J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol"},{"key":"R17-12-20260313","doi-asserted-by":"crossref","first-page":"189","DOI":"10.4103\/0971-9261.141995","article-title":"Gonadal germ cell tumors in children and adolescents","volume":"19","author":"Cecchetto","year":"2014","journal-title":"J. Indian Assoc. Pediatr. Surg"},{"key":"R18-12-20260313","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1053\/jpsu.2003.50100","article-title":"Malignant retroperitoneal and abdominal germ cell tumors: an intergroup study","volume":"38","author":"Billmire","year":"2003","journal-title":"J. Pediatr. Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026122201029X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026122201029X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107783","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T11:01:14Z","timestamp":1773399674000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2022.107783"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":14,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2022.107783","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}