{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T10:29:04Z","timestamp":1774434544244,"version":"3.50.1"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The most common causes of hematuria are lower urinary tract infections, especially of the bladder, urolithiasis, urogenital tumors or benign prostatic hyperplasia; consequently, this condition presents the greatest clinical challenge due to its broad clinical spectrum, hematuria is an atypical form of presentation of testicular tumors, with very few cases reported in the literature, reaffirming the importance of a complete examination when approaching hematuria in the emergency department.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We present a case of a 31-year-old patient who presented to the emergency department with macroscopic hematuria of 5 weeks of evolution, showing on examination a mass in the left testicle. Imaging studies showed bilateral pulmonary metastatic lesions and retroperitoneal lymph node activity with a retrocaval conglomerate infiltrating the left ureter, for which a radical left orchiectomy and multiple procedures were performed to resolve the hematuria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Macroscopic hematuria in adolescents or young adults is an infrequent cause of admission to the Emergency Department with a large list of differential diagnoses both benign and malignant so it is necessary to perform exhaustive studies in its approach, when young patients present with a painless testicular mass, it is important to keep testicular cancer within the differential diagnoses, metastatic disease is a rare form of presentation in this type of tumors. The relevance of this clinical case lies in the fact that hematuria was the main symptom that brought the patient to the emergency department, so we must not forget that macroscopic hematuria should be extensively studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>When approaching a patient with macroscopic hematuria, the clinical history and physical examination is extremely important to provide the best possible care and focus the treatment properly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2022.107799","type":"journal-article","created":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T04:03:49Z","timestamp":1669176229000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Macroscopic hematuria as an initial symptom of testicular cancer, an unusual presentation and initial management. A case report"],"prefix":"10.1097","volume":"101","author":[{"given":"Ori\u00f3n Erenh\u00fa Rodriguez","family":"Gonzalez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgar Ivan Bravo","family":"Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Gad\u00fa Campos","family":"Salcedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-24-20260313","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.eururo.2018.03.008","article-title":"Who should be investigated for haematuria? Results of a contemporary prospective observational study of 3556 patients","volume":"74","author":"Tan","year":"2018","journal-title":"Eur. Urol"},{"key":"R2-24-20260313","first-page":"801","article-title":"The investigation of hematuria","volume":"115","author":"Bolenz","year":"2018","journal-title":"Dtsch. Arztebl. Int"},{"key":"R3-24-20260313","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.juro.2017.06.083","article-title":"Variation in the diagnostic evaluation among persons with hematuria: influence of gender, race and risk factors for bladder cancer","volume":"198","author":"Ark","year":"2017","journal-title":"J. Urol"},{"key":"R4-24-20260313","first-page":"MC7949432","article-title":"D., Ryan J., Harris J., Cheema I., Visible haematuria-an unusual presentation of metastatic testicular mixed germ cell tumour, BMJ Case Rep. 14 (3) (2021 ), e241056, https:doi.org10.1136bcr-2020-241056.","volume":"PMCID","author":"Sugrue","year":"33692071","journal-title":"PMID:"},{"key":"R5-24-20260313","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.eururo.2019.10.003","article-title":"The complex and nuanced care for early-stage testicular cancer: lessons from the European Association of Urology and american urological association testis cancer guidelines","volume":"77","author":"Bagrodia","year":"2020","journal-title":"Eur. 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