{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T12:53:46Z","timestamp":1774443226530,"version":"3.50.1"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T00:00:00Z","timestamp":1702512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Leiomyomas are rare benign mesenchymal tumors originating from smooth muscle cells. Scrotal leiomyomas, in particular, are exceptionally rare, with a prevalence rate of 1 in 1000 among all scrotal tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This case Report has been Reported in line with SCARE Criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of the case:<\/jats:title>\n                    <jats:p>A 55-year-old Caucasian male presented with a five-year history of painless scrotal swelling, gradually increasing in size. Clinical examination revealed a non-tender oval lump on the right hemiscrotum. The right testis and cord structures were distinguishable from the mass. While the initial clinical assessment was suggestive of a sebaceous cyst, further evaluation was performed. A wide local excision of the lump was performed and sent for histopathological evaluation. Microscopy indicated a well-circumscribed, non-atypical leiomyoma with no necrosis or increased mitosis, providing us with a definitive diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Scrotal leiomyomas are a rare subset of genital leiomyomas, mostly found in middle-aged Caucasian men. Pathological examination is the mainstay to distinguish these tumors into typical and atypical leiomyomas, impacting treatment decisions. Simple surgical excision is curative, and Irradiation is contraindicated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Scrotal leiomyomas should be considered in the differential diagnosis of scrotal masses. This case emphasizes the necessity of wide local excision, with adequate clearance, and regular follow-up to rule out recurrence, particularly given the potential for atypia and progression to leiomyosarcoma. The prognosis overall is good as recurrence rates are low.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2023.109178","type":"journal-article","created":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T11:31:31Z","timestamp":1702726291000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Rare case of a scrotal leiomyoma-a diagnostic dilemma: A case report"],"prefix":"10.1097","volume":"114","author":[{"given":"Sneha","family":"Makkapati","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Venkatasubramanian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muralidharan","family":"M","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"3","key":"R1-90-20260325","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1158\/ajc.1937.435","article-title":"Solitary cutaneous and subcutaneous leiomyoma","volume":"29","author":"Stout,","year":"1937","journal-title":"Am. J. Cancer"},{"issue":"4","key":"R2-90-20260325","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1001\/archderm.1983.01650280086023","article-title":"Leiomyoma of the scrotum","volume":"119","author":"Livne,","year":"1983","journal-title":"Arch. Dermatol."},{"issue":"3","key":"R3-90-20260325","first-page":"243","article-title":"Leiomyoma of scrotum: a rare case report","volume":"10","author":"Rana,","year":"2015","journal-title":"Iran. J. Pathol."},{"issue":"3","key":"R4-90-20260325","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4103\/HMJ.HMJ_65_18","article-title":"Scrotal leiomyoma","volume":"12","author":"Adebayo,","year":"2019","journal-title":"Hamdan Med. J."},{"key":"R5-90-20260325","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0022-5347(17)58680-2","article-title":"Solitary leiomyomas arising from the tunica dartos scroti","volume":"116","author":"Siegal,","year":"1976","journal-title":"J. Urol."},{"issue":"6","key":"R6-90-20260325","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1365-2559.1991.tb01479.x","article-title":"Smooth muscle tumors of the external genitalia: clinicopathological analysis of a series","volume":"18","author":"Newman,","year":"1991","journal-title":"Histopathology"},{"issue":"1","key":"R7-90-20260325","doi-asserted-by":"crossref","first-page":"72","DOI":"10.4103\/0377-4929.40405","article-title":"Leiomyoma of scrotum","volume":"51","author":"Sherwani,","year":"2008","journal-title":"Indian J. Pathol. Microbiol."},{"key":"R9-90-20260325","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ijscr.2020.01.057","article-title":"Typical leiomyoma of the scrotum: a rare case report","volume":"67","author":"Fakhralddin,","year":"2020","journal-title":"Int. J. Surg. Case Rep."}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026122301307X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026122301307X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2023.109178","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T10:13:49Z","timestamp":1774433629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2023.109178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":8,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2023.109178","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-10-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}