{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T13:49:08Z","timestamp":1775656148881,"version":"3.50.1"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T00:00:00Z","timestamp":1702857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Introduction and importance:<\/jats:title>\n Acute appendicitis is a common surgical emergency, often resulting in perforation and increased morbidity. Up to 55 % of children with complicated appendicitis may experience a complication such as infection, bowel obstruction, or unplanned hospital re-admission (Blakely et al., 2011 [23]). However, the development of infectious spondylodiscitis following appendectomy is an extremely rare complication, particularly in pediatric patients. We present the first reported case of lumbar spondylodiscitis occurring post-perforated appendicitis in a 14-year-old female, highlighting the importance of recognizing and managing uncommon complications.<\/jats:p>\n <\/jats:sec>\n \n Case presentation:<\/jats:title>\n \n A previously healthy 14-year-old female underwent urgent appendectomy for perforated appendicitis. Postoperatively, she developed severe back pain and immobility. Imaging revealed early lumbar discitis, and\n Pseudomonas aeruginosa<\/jats:italic>\n was isolated from the surgical site. The patient received multiple antibiotic regimens, including vancomycin, ceftazidime, and meropenem, resulting in clinical improvement.\n <\/jats:p>\n <\/jats:sec>\n \n Clinical discussion:<\/jats:title>\n Infectious spondylodiscitis is typically hematogenously spread or due to direct inoculation. In this case, the spread from a contiguous focus of infection without vascular insufficiency is suspected. The coexistence of appendicitis and spondylodiscitis poses diagnostic challenges, requiring a multidisciplinary approach for accurate diagnosis and appropriate treatment.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n This unique case highlights the need for vigilance in recognizing rare complications of appendicitis, such as infectious spondylodiscitis. Early diagnosis and tailored antibiotic therapy are crucial for optimal outcomes. Further research is needed to explore the underlying mechanisms and risk factors associated with this rare complication.<\/jats:p>\n <\/jats:sec>\n \n Highlights<\/jats:title>\n <\/jats:sec>","DOI":"10.1016\/j.ijscr.2023.109184","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T04:46:57Z","timestamp":1703738817000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Spondylodiscitis following perforated acute appendicitis in a 14-year-old female: A case report"],"prefix":"10.1097","volume":"115","author":[{"given":"Marwa","family":"AlTarayra","sequence":"first","affiliation":[{"name":"General Surgery, Governmental Hebron Hospital, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil N.M.","family":"Abuzaina","sequence":"additional","affiliation":[{"name":"General Surgery, Hebron University, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ammar W.M.","family":"Hassouneh","sequence":"additional","affiliation":[{"name":"Diagnostic Radiology, Governmental Hebron Hospital, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osama Y.A.","family":"Aljabarein","sequence":"additional","affiliation":[{"name":"General Surgery, Governmental Hebron Hospital, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"9","key":"R2-8-20260408","doi-asserted-by":"crossref","first-page":"135","DOI":"10.2147\/PHMT.S155302","article-title":"Perforation risk in pediatric appendicitis: assessment and management","volume":"26","author":"Howell,","year":"2018","journal-title":"Pediatric Health Med. 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Surg."},{"issue":"6","key":"R10-8-20260408","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1001\/archsurg.2011.6","article-title":"Early vs interval appendectomy for children with perforated appendicitis","volume":"146","author":"Blakely,","year":"2011","journal-title":"Arch. Surg."}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261223013135?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261223013135?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2023.109184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T13:00:24Z","timestamp":1775653224000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2023.109184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":8,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2023.109184","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"2023-11-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}