{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T13:49:00Z","timestamp":1775656140110,"version":"3.50.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T00:00:00Z","timestamp":1704931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Granulosa cell tumors (GCTs) are rare tumors, which mostly affect the ovaries. GCTs are classified into two types: juvenile and adult. Adult testicular GCTs are potentially malignant sex cord-stromal tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Here, we report a case of a 63-year-old man who presented with a right testicular nodule. Testicular ultrasound showed a hypoechoic tissue mass, measuring 3 cm and hyper vascularized in the color Doppler. A radical orchidectomy was performed. Histology showed a typical adult-type Granulosa cell tumor. After 12 months follow up, the patient is doing well and disease-free.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>According to our case and a review of the literature, this type of tumor is an uncommon and slow-growing neoplasm. The diagnosis is confirmed by histology, treatment is based on surgery, radical orchidectomy. Long-term follow-up of patients is essential because distant metastases may emerge late in the clinical course.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case report adds valuable insights to the limited literature on adult testicular Granulosa cell tumors. Radical orchidectomy remains the optimal treatment, and early diagnosis, coupled with surgery, significantly enhances prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109259","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T18:42:47Z","timestamp":1705689767000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A testicular mass found to be a rare testicular adult-type granulosa cell tumor: A case report and literature review"],"prefix":"10.1097","volume":"115","author":[{"given":"Fatima","family":"Rezzoug","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hind","family":"Chibani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soufia","family":"El Ouardani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ouissam","family":"Al Jarroudi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sami Aziz","family":"Brahmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Said","family":"Afqir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-58-20260408","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1016\/S0893-3952(22)04460-X","article-title":"Sex cord-stromal tumors of the ovaryand testis: their similarities and differenceswith consideration of selected problems","volume":"18","author":"Young,","year":"2005","journal-title":"Mod Pathol"},{"key":"R2-58-20260408","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/his.13115","article-title":"The World Health Organization 2016 classification of testicular non-germ cell tumours: a review and update from the International Society of Urological Pathology Testis Consultation Panel","volume":"70","author":"Idrees,","year":"2017","journal-title":"Histopathology"},{"issue":"2","key":"R3-58-20260408","doi-asserted-by":"crossref","first-page":"e101","DOI":"10.5489\/cuaj.10176","article-title":"A rare testicular solid mass in children: juvenile granulosa cell tumour of testis","volume":"6","author":"Couture,","year":"2012","journal-title":"Can. Urol. Assoc. J."},{"key":"R4-58-20260408","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1007\/s00432-020-03326-3","article-title":"Risk factors and treatment outcomes of 239 patients with testicular granulosa cell tumors: a systematic review of published case series data","volume":"146","author":"Grogg,","year":"2020","journal-title":"J. Cancer Res. Clin. Oncol."},{"issue":"1","key":"R5-58-20260408","first-page":"44","article-title":"Feminizing tumors of the testis: general review with case report of granulosa cell tumor of the testis","volume":"14","author":"Laskowski,","year":"1952","journal-title":"Endokrynol. Pol."},{"key":"R6-58-20260408","doi-asserted-by":"crossref","first-page":"143","DOI":"10.5858\/2009-0512-RSR.1","article-title":"Adult testicular granulosa cell tumor: a review of the literature for clinicopathologic predictors of malignancy","volume":"135","author":"Hanson,","year":"2011","journal-title":"Arch. Pathol. Lab. 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