{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:19:40Z","timestamp":1786990780029,"version":"build-2736575974"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Intracranial glioependymal cysts are an uncommon type of neuroepithelial cyst and are encountered much less frequently than arachnoid cysts. These cysts primarily manifest within the parenchyma of the brain, although exceedingly rare instances have been reported in the lateral ventricles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We present a highly unusual case of a glioependymal cyst in a 7-year-old girl. The glioependymal cyst was located in the midline in the suprasellar region and extended to the upper clivus region. Its only manifestation was precocious puberty. We performed endoscopic fenestration of the cyst, leading to a return of hormonal levels to normal and a slight reduction in cyst size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>A comprehensive search of the Medline database revealed only a few documented cases of glioependymal cysts (fewer than 30 cases). Remarkably, the majority (if not all) were located laterally rather than in the midline of the brain. Endoscopic fenestration and biopsy are effective and confirm the diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This instance of a rare glioependymal cyst located in the midline, spanning the suprasellar and retrosellar regions, is an uncommon occurrence. Its sole presentation was precocious puberty. The successful management of this condition was achieved through an endoscopic approach, leading to the normalization of endocrine abnormalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109360","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T06:14:02Z","timestamp":1708496042000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Giant supra and retrosellar glioependymal cyst presenting with only precocious puberty. Clinical study and review of the literature"],"prefix":"10.1097","volume":"116","author":[{"given":"Hassan","family":"Kadri","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Children's University Hospital, Faculty of Medicine, Damascus University, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazen","family":"Dughly","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Damascus Hospital, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad Shehadeh","family":"Agha","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine, Damascus University, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghiath","family":"Hamed","sequence":"additional","affiliation":[{"name":"Amana Pathology Lab, Damascus, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raed","family":"Abouharb","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine, Damascus University, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rostom","family":"Mackieh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Children's University Hospital, Faculty of Medicine, Damascus University, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-46-20260326","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1007\/s00701-018-3566-0","article-title":"Intracranial glioependymal (neuroglial) cysts: a systematic review","volume":"160","author":"Robles,","year":"2018","journal-title":"Acta Neurochir."},{"issue":"1","key":"R2-46-20260326","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1186\/s12885-020-07570-1","article-title":"Intraventricular neuroepithelial tumors: surgical outcome, technical considerations and review of literature","volume":"20","author":"Aftahy,","year":"2020","journal-title":"BMC Cancer"},{"issue":"5","key":"R3-46-20260326","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int J Surg Lond Engl."},{"key":"R4-46-20260326","first-page":"1","article-title":"Neuroendoscopic fenestration of glioependymal cysts to the ventricle: report of 3 cases","author":"Alvarado,","year":"2018","journal-title":"J. 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