{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T11:37:32Z","timestamp":1784893052586,"version":"3.55.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Despite being the longest and containing a greater proportion of the gastrointestinal tract's mucosal surface area, the small bowel is where &lt;2 % to 5 % of gastrointestinal cancers can occur. Peutz-Jeghers syndrome is the rarest risk factor for the development of small intestinal cancers. Here we report a case of perforated poorly differentiated adenocarcinoma of the jejunum for which Peutz-Jeghers syndrome is identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 25-year-old male patient presented to the emergency department with generalized peritonitis caused by a perforated jejunal mass. The patient underwent an emergency exploratory laparotomy. There was 800 ml of thin pus in the peritoneal cavity and 5 cm by 6 cm perforated mass over the jejunum which extends to the mesentery. Palpable intraluminal polyps with an inverted serosal surface for some of them were identified. The pus was sucked out, and the mass was resected with its mesenteric lymph nodes and segments containing polyps. Subsequently, end-to-end hand-sewn anastomosis was performed, and the abdomen was closed. The histopathology report showed poorly differentiated adenocarcinoma, stage IIIC (PT3, PN2), and Peutz-Jeghers polyps, suggesting Peutz-Jeghers syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Even though small bowel malignancy is a rare entity, early detection is a challenging issue, especially when it happens below the ligaments of the trietz. Surgical resection offers the only potential cure for small bowel malignancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We conclude that patients with long-term, nonspecific abdominal complaints are good candidates for evaluation and investigation without overlooking small bowel malignancy. Peutz-Jeghers syndrome was a potential risk factor in our case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109519","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T05:18:16Z","timestamp":1710134296000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Poorly differentiated adenocarcinoma of the jejunum in a patient with Peutz-Jeghers syndrome: A case report"],"prefix":"10.1097","volume":"117","author":[{"given":"Fufa","family":"Miresa","sequence":"first","affiliation":[{"name":"Department of Surgery, College of Health and Medical Science, Haramaya University, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Badhaasaa","family":"Beyene","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Health and Medical Science, Haramaya University, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munewor","family":"Abdulhadi","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Health and Medical Science, Haramaya University, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulaziz","family":"Mohamud","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Health and Medical Science, Haramaya University, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anteneh","family":"Belachew","sequence":"additional","affiliation":[{"name":"Department of Pathology, College of Health and Medical Science, Haramaya University, Harar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R3-61-20260423","first-page":"1","article-title":"An Unusual Case of Peutz - Jeghers Syndrome With Polyposis-associated Adenomatous Change","volume":"11","author":"Shetty,","year":"2020"},{"issue":"7","key":"R6-61-20260423","first-page":"1","article-title":"Peutz-Jeghers Syndrome Presenting With Anemia: A Case Report","volume":"14","author":"Shakil,","year":"2022"},{"key":"R8-61-20260423","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.ijscr.2021.01.053","article-title":"CASE REPORT - OPEN ACCESS International Journal of Surgery Case Reports Peutz-Jeghers syndrome in a woman presenting as intussusception: a case report","volume":"79","author":"Syarifuddin,","year":"2021","journal-title":"Int. J. Surg. Case Rep. [Internet]"},{"issue":"1","key":"R10-61-20260423","first-page":"124","article-title":"Peutz Jeghers Syndrome Revealed by Intestinal Intussuception: A Case Report and a Review of the Literature","volume":"4","author":"Sabrine,","year":"2020"},{"issue":"5","key":"R11-61-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg. Lond. Engl."},{"key":"R12-61-20260423","first-page":"804","article-title":"Shackelford's Surgery of the Alimentary Tract 8th Ed","volume":"2","author":"Zuidema,","year":"2019"},{"key":"R14-61-20260423","article-title":"Case Report Seven-Year Follow-up of Peutz-Jeghers Syndrome","volume":"2016","author":"Mozaffari,","year":"2016"},{"issue":"7","key":"R15-61-20260423","first-page":"154","article-title":"Peutz-Jeghers Syndrome: A Case Report","volume":"12","author":"Poudel,","year":"2021"},{"issue":"1","key":"R18-61-20260423","first-page":"3","article-title":"Jejunal Adenocarcinoma: A Rare Cause of Small Bowel Obstruction Case Presentation","volume":"14","author":"Patel,","year":"2022"},{"issue":"9","key":"R20-61-20260423","first-page":"1109","article-title":"Small Bowel Adenocarcinoma, Version 1.2020","volume":"17","author":"Adenocarcinoma,","year":"2023"},{"issue":"1","key":"R21-61-20260423","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.dld.2017.09.123","article-title":"Small bowel adenocarcinoma: French intergroup clinical practice guidelines for diagnosis, treatments and follow-up (SNFGE, FFCD)","volume":"50","author":"Locher,","year":"2018","journal-title":"Dig. Liver Dis. [Internet]"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224003006?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224003006?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2024.109519","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T21:02:18Z","timestamp":1776978138000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2024.109519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":11,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2024.109519","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2024-02-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}