{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T21:40:59Z","timestamp":1776980459367,"version":"3.51.4"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004423","name":"World Health Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004423","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Interstitial pregnancies are a rare form of ectopic pregnancy with life threatening consequences. Thus, the aim of this report is to shed light on the importance of early diagnosis for optimal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Herein, we present a case of an interstitial ectopic pregnancy in a 31-year-old Syrian female who presented only with mild non-specific abdominal pain. The ultrasound showed a gestational sac in the right horn of the uterus non-communicating with the endometrial cavity suggesting an interstitial ectopic pregnancy. Cornual excision and salpingectomy were performed with laparotomy instead of laparoscopy due to resource-limited facilities. Follow-up with serum human chorionic gonadotropin \u03b2-HCG continued until the hormone levels became undetectable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Interstitial ectopic pregnancies can present with non-classic symptoms. Ultrasonographic evaluation for lower abdominal pain in women at the first trimester is essential to detect interstitial ectopic pregnancies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Early diagnosis is key to prevent the life threatening progression of interstitial pregnancy, so this diagnosis should be kept in mind in women presenting with first trimester abdominal pain and\/or vaginal bleeding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109529","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T03:24:47Z","timestamp":1710732287000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Interstitial ectopic pregnancy: A rare case report"],"prefix":"10.1097","volume":"117","author":[{"given":"Majd","family":"Sabbagh","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Hospital of Obstetrics and Gynecology in Damascus, Faculty of Medicine, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nehad","family":"Othman","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Hospital of Obstetrics and Gynecology in Damascus, Faculty of Medicine, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salah","family":"Chaikha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rehab","family":"Sukkar","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University Hospital of Obstetrics and Gynecology in Damascus, Faculty of Medicine, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal","family":"alToto","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"alQudsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"4","key":"R1-68-20260423","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1097\/AOG.0b013e3182113c10","article-title":"Trends in ectopic pregnancy mortality in the United States: 1980-2007","volume":"117","author":"Creanga,","year":"2011","journal-title":"Obstet. 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Engl."},{"issue":"6","key":"R8-68-20260423","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s13224-017-1078-0","article-title":"Interstitial and cornual ectopic pregnancy: conservative surgical and medical management.","volume":"68","author":"Dagar","year":"2018","journal-title":"J. Obstet. Gynaecol. India."},{"issue":"9","key":"R9-68-20260423","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.3390\/medicina58091160","article-title":"The very first Romanian unruptured 13-weeks gestation tubal ectopic pregnancy","volume":"58","author":"Ilea,","year":"2022","journal-title":"Medicina (Kaunas)"},{"issue":"18","key":"R10-68-20260423","doi-asserted-by":"crossref","first-page":"9781","DOI":"10.3390\/ijerph18189781","article-title":"Interstitial ectopic pregnancy: the role of mifepristone in the medical treatment","volume":"18","author":"Stabile,","year":"2021","journal-title":"Int. J. Environ. Res. 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