{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:15:12Z","timestamp":1789532112925,"version":"build-2803163510"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Synovial lipomatosis is a rare disease that often results in joint discomfort, swelling, and effusion. Only a few reported cases have been documented so far.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We reported a 50-year-old woman with synovial lipomatosis of the ankle joint. The patient presented with left ankle pain since the least two years, accompanied by swelling and redness. Physical examination demonstrated swollen ankle with warmth palpation. Magnetic resonance imaging (MRI) demonstrated hyperintensity of the ankle joint on the posterior and anterolateral side, thickening of the synovium, and bone marrow edema around the talar bone, surrounding the sinus tarsi. Histopathological examination demonstrated fatty tissues with nonspecific inflammation, suggesting synovial lipomatosis. We performed synovectomy, and the pain did not recur at 1 year of follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Synovial lipomatosis is a highly uncommon benign condition. Histopathologically, synovial lipomatosis is characterized by notable adipocyte infiltration into the subsynovial tissue and a villous or frond-like morphology of the synovium. It also features transversely hyperplastic synovial lining cells.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Synovial lipomatosis of the ankle joint is a rare entity. Further studies are required to investigate this disease and its management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109694","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T02:24:21Z","timestamp":1713925461000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Synovial lipomatosis of the ankle joint: A rare case report"],"prefix":"10.1097","volume":"119","author":[{"given":"Ihsan","family":"Oesman","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelina","family":"Kodrat","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anissa Feby","family":"Canintika","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilham Suryo Wibowo","family":"Antono","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indra Kusuma","family":"Jaya","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin Jonathan","family":"Adhimulia","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"6","key":"R1-43-20260422","article-title":"Results of arthroscopic synovectomy for treatment of synovial lipomatosis (lipoma arborescens) of the knee","volume":"31","author":"Malkoc","year":"2018","journal-title":"J. Knee Surg."},{"issue":"5","key":"R2-43-20260422","doi-asserted-by":"crossref","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"Int. J. Surg."},{"key":"R3-43-20260422","article-title":"Synovial lipomatosis: histopathologic features in a series of five cases","volume":"18","author":"AbdullGaffar","year":"2023","journal-title":"Int. J. Surg. Pathol."},{"issue":"1","key":"R4-43-20260422","doi-asserted-by":"crossref","DOI":"10.1007\/s00256-007-0399-y","article-title":"Synovial and tenosynovial lipoma arborescens of the ankle in an adult: a case report","volume":"37","author":"Babar","year":"2008","journal-title":"Skelet. Radiol."},{"issue":"8","key":"R5-43-20260422","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/RHU.0b013e3181c38759","article-title":"The role of magnetic resonance imaging for the diagnosis of lipoma arborescens in polyarthritic patients with persistent single-joint effusion","volume":"15","author":"Nguyen","year":"2009","journal-title":"J. Clin. Rheumatol."},{"key":"R6-43-20260422","doi-asserted-by":"crossref","DOI":"10.1111\/1346-8138.15003","article-title":"Synovial lipomatosis in the interphalangeal joint of the great toe","volume":"46","author":"Matsuda","year":"2019","journal-title":"J. Dermatol."},{"issue":"1","key":"R7-43-20260422","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jos.2016.11.002","article-title":"Lipoma arborescens in bilateral knee joints accompany gouty tophi: a case-based review of the literature","volume":"24","author":"Hayashi","year":"2019","journal-title":"J. Orthop. Sci."},{"issue":"4","key":"R8-43-20260422","first-page":"22","article-title":"Synovial lipomatosis with chondroblastoma in an 8-year-old female: a previously unreported entity","volume":"9","author":"Khatri","year":"2019","journal-title":"J. Orthop. Case Rep. [Internet]"},{"issue":"00","key":"R9-43-20260422","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/RHU.0000000000000833","article-title":"Lipoma arborescens associated with psoriatic arthritis in an adolescent boy a case report and review of the literature","volume":"00","author":"Batu","year":"2018","journal-title":"J. Clin. Rheumatol. [Internet]"},{"issue":"10","key":"R10-43-20260422","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1007\/s00256-017-2708-4","article-title":"Isolated peroneal tenosynovial lipoma arborescens: multimodality imaging features","volume":"46","author":"Wang","year":"2017","journal-title":"Skelet. Radiol."},{"issue":"4","key":"R11-43-20260422","doi-asserted-by":"crossref","DOI":"10.7547\/15-140","article-title":"Synovial lipoma of the subtalar joint: a rare case report","volume":"107","author":"Whitaker","year":"2017","journal-title":"J. Am. Podiatr. Med. 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