{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:24:35Z","timestamp":1785522275324,"version":"3.56.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Embryonal Rhabdomyosarcoma is a rare form of sarcoma mainly seen in children and adolescents. In the specific case of the cervix, embryonal Rhabdomyosarcoma is an extremely rare mesenchymal tumor, accounting for &lt;1 % of all cervical cancers. This highly malignant tumor mainly affects adolescents and young adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We describe the case of a 29-year-old woman with embryonal rhabdomyosarcoma of the cervix, which manifested as an exophytic cervical mass. Histopathological and immunohistochemical findings confirmed the presence of embryonal rhabdomyosarcoma of the cervix. This patient was successfully treated with a combination of neoadjuvant chemoradiotherapy, total abdominal hysterectomy with bilateral ovary transposition, and adjuvant chemoradiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Embryonal Rhabdomyosarcoma of the cervix may manifest by vaginal bleeding, a cervical mass and pelvic symptoms. The diagnosis is confirmed by histopathology and immunohistochemistry. With multimodal treatment including surgery, chemotherapy and radiotherapy, outcomes improve for patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Uterine cervix embryonal RMS is an uncommon cancer in adult patients. While rare, it should be considered as a potential diagnosis in patients presenting with vaginal bleeding and a significant cervical polyp. Histopathology, complemented by relevant immunohistochemistry, is crucial for accurately detecting the tumor and guiding appropriate management strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109742","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T22:18:01Z","timestamp":1715206681000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["A challenging diagnosis and treatment of embryonal rhabdomyosarcoma in the cervix of an adult woman: A surgical case report"],"prefix":"10.1097","volume":"119","author":[{"given":"Hamza","family":"Messaoudi","sequence":"first","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelhamid","family":"Benlghazi","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abderrahim","family":"Elktaibi","sequence":"additional","affiliation":[{"name":"Department of Pathology Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moad","family":"Belouad","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elhassani","family":"Moulay Mehdi","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaouad","family":"Kouach","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"12","key":"R1-82-20260422","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1055\/s-0032-1328076","article-title":"18-year-old woman with an embryonal rhabdomyosarcoma of the uterus in statu nascendi","volume":"72","author":"Strahl","year":"2012","journal-title":"Geburtshilfe Frauenheilkd."},{"key":"R2-82-20260422","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/8459566","article-title":"A rare case of embryonal rhabdomyosarcoma of the uterine cervix","volume":"2022","author":"Bahall","year":"2022","journal-title":"Case Reports in Pathology"},{"issue":"2","key":"R3-82-20260422","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jpag.2019.12.002","article-title":"DICER1-related embryonal rhabdomyosarcoma of the uterine corpus in a prepubertal girl","volume":"33","author":"Dural","year":"2020","journal-title":"J. Pediatr. Adolesc. Gynecol."},{"issue":"5","key":"R4-82-20260422","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"Int. J. Surg."},{"issue":"5","key":"R5-82-20260422","first-page":"784","article-title":"Rabdomiosarcoma embrionario botrioide de \u00fatero","volume":"82","author":"Aracil","year":"2022","journal-title":"Medicina (Buenos Aires)"},{"issue":"4pt2","key":"R6-82-20260422","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1046\/j.1341-8076.2002.t01-1-00044.x-i1","article-title":"Embryonal rhabdomyosarcoma of the uterus associated with uterine inversion in an adolescent: a case report and published work review","volume":"34","author":"Da Silva","year":"2008","journal-title":"J. Obstet. Gynaecol. 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