{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:16:31Z","timestamp":1789186591746,"version":"build-2803163510"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T00:00:00Z","timestamp":1715558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>A pituitary abscess (PA) is an extremely rare disease. It is characterized by the presence of an infected purulent collection within the Sella turcica. PAs are categorized in two categories: primary, when the pituitary is normal before the infection, or secondary, when there is a pre-existing sellar pathology (e.g., pituitary adenoma, Rathke's cleft cysts, or craniopharyngioma), meningitis, paranasal sinusitis, or head surgery, which may be indicative of the source of infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>\n                      We presented a case of a 52-year-old male with visual disturbances. Both a computerized tomography scan and magnetic resonance imaging revealed a sellar mass lesion, initially suspected to be a pituitary tumor. During transsphenoidal surgery for excision of the pituitary mass, an amount of pus was drained, indicating a pituitary abscess, which was confirmed by positive\n                      <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                      colonies in the culture.\n                    <\/jats:p>\n                    <jats:p>After surgery, the patient received antibiotic treatment for 12 weeks. After two years of follow-up, the patient remained free of complications and did not require hormone replacement therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>In previous research, there were a total of 488 patients, of those, 318 were primary pituitary abscess. Preoperative diagnosis is still difficult due to a combination of nonspecific symptoms and imaging findings. Endonasal trans-sphenoidal pus evacuation, culture, and individualized antibiotic therapy are available treatment options.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Pituitary abscess is a rare illness, but it should always be considered when evaluating a patient with a fast visual decline. Following the diagnosis, surgery and antibiotics should be started immediately. Proper therapy usually yields a positive effect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109753","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T11:52:43Z","timestamp":1715773963000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Primary pituitary abscess with atypical imaging features: A rare case report"],"prefix":"10.1097","volume":"119","author":[{"given":"Raghad","family":"Samha","sequence":"first","affiliation":[{"name":"Faculty of Medicine, AlBaath University, Homs, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Raya","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Kalamoon, Damascus, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marah","family":"Mansour","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tartous University, Tartous, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal","family":"Mansour","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tishreen University, Lattakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Ayham","family":"Mohsen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Neurosurgery, Damascus University Hospital, Damascus, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basel","family":"Alromhain","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Neurosurgery, Al Assad University Hospital, Damascus, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-90-20260422","doi-asserted-by":"crossref","DOI":"10.12659\/AJCR.936743","article-title":"A pituitary abscess caused by Morganella morganii: a case report","volume":"23","author":"Alelyani","year":"2022","journal-title":"Am. J. Case Rep."},{"issue":"1","key":"R2-90-20260422","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1186\/s13023-023-02788-1","article-title":"Pituitary abscess: a case report and systematic review of 488 cases","volume":"18","author":"Stringer","year":"2023","journal-title":"Orphanet J. Rare Dis."},{"key":"R3-90-20260422","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2016-217912","article-title":"Pituitary abscess","volume":"2017","author":"Al Salman","year":"2017","journal-title":"BMJ Case Rep."},{"key":"R4-90-20260422","doi-asserted-by":"crossref","first-page":"379","DOI":"10.5603\/EP.a2022.0022","article-title":"Pituitary abscess in an eight-year-old girl \u2014 diagnostic difficulties","volume":"73","author":"Moszczy\u0144ska","year":"2022","journal-title":"Endokrynol. Pol."},{"key":"R5-90-20260422","first-page":"206","article-title":"Primary pituitary tubercular abscess: a case report","volume":"57","author":"Roka","year":"2019","journal-title":"JNMA J. Nepal Med. Assoc."},{"issue":"5","key":"R6-90-20260422","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"Collaborators. The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"International Journal of Surgery"},{"issue":"5","key":"R7-90-20260422","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"Int. J. Surg. Lond. Engl."},{"issue":"3","key":"R8-90-20260422","doi-asserted-by":"crossref","first-page":"565","DOI":"10.3390\/medicina59030565","article-title":"Pituitary abscess: a challenging preoperative diagnosis\u2014a multicenter study","volume":"59","author":"Mallereau","year":"2023","journal-title":"Medicina"},{"key":"R9-90-20260422","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.4103\/neuroindia.NI_997_16","article-title":"Primary pituitary abscess in preadolescence mimicking a sellar mass","volume":"65","author":"Akbarian-Tefaghi","year":"2017","journal-title":"Neurol. India"},{"key":"R10-90-20260422","doi-asserted-by":"crossref","first-page":"431","DOI":"10.31083\/j.jin2002045","article-title":"Abnormal magnetic resonance imaging of the sellar region and its surroundings in patients with pituitary abscess","volume":"20","author":"Wu","year":"2021","journal-title":"J. Integr. Neurosci."},{"key":"R11-90-20260422","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.wneu.2017.01.077","article-title":"Case report of a primary pituitary abscess and systematic literature review of pituitary abscess with a focus on patient outcomes","volume":"101","author":"Agyei","year":"2017","journal-title":"World Neurosurg."},{"issue":"11","key":"R12-90-20260422","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2021-246776","article-title":"Case of an atypical pituitary abscess","volume":"14","author":"Bloomer","year":"2021","journal-title":"BMJ Case Rep."},{"key":"R13-90-20260422","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.4103\/0028-3886.329622","article-title":"A rare case of primary pituitary tubercular abscess mimicking a pituitary adenoma","volume":"69","author":"Gotecha","year":"2021","journal-title":"Neurol. India"},{"key":"R14-90-20260422","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s11060-013-1285-1","article-title":"Etiology, prognosis, and management of secondary pituitary abscesses forming in underlying pituitary adenomas","volume":"117","author":"Awad","year":"2014","journal-title":"J. Neuro-Oncol."},{"key":"R15-90-20260422","first-page":"611","article-title":"Diagnosis and management of pituitary abscess: a case series and review of the literature","volume":"23","author":"Altas","year":"2013","journal-title":"Turk. Neurosurg."},{"key":"R16-90-20260422","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s00381-021-05052-8","article-title":"Primary pituitary abscess in an adolescent female patient: case report, literature review, and operative video","volume":"37","author":"Sherrod","year":"2021","journal-title":"Childs Nerv. 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