{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T13:09:12Z","timestamp":1774444152871,"version":"3.50.1"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Giant hepatic haemangioma (GHH) is defined as a hepatic haemangioma (HH) of &gt;10 cm in diameter. Its association with thrombocytopenia and consumption coagulopathy is quite rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Here, we present a case of a 39-year-old man with a rapidly enlarging 25-cm GHH arising from the entire left hemiliver. Laboratory findings suggested pancytopenia but normal liver and renal functions. He was diagnosed with Kasabach-Merritt syndrome (KMS). After three units of aphaeretic platelet transfusion, the patient underwent left hepatectomy. Postoperative recovery was uneventful, and his regular follow-up revealed no recurrence even after two years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>HH predominantly affects females, but males can also be affected, as seen in this case. With observation, it can grow over time, particularly in patients under 50 years of age. Surgical management should be considered when HH causes symptoms or is larger than 10 cm. The evolving understanding of GHH and the critical role of surgery are important, particularly when they complicate haematological or coagulation profiles and lead to thrombocytopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our case report highlights the significance of surgical intervention in GHH, and a disease-free outcome can be expected for patients with this condition in the future. To our knowledge, this is the first such case report from Bangladesh.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109795","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T13:49:43Z","timestamp":1716472183000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Surgical management of a 25-cm giant hepatic haemangioma: First case report from Bangladesh with literature review"],"prefix":"10.1097","volume":"120","author":[{"given":"Hashim","family":"Rabbi","sequence":"first","affiliation":[{"name":"Department of Hepato-Pancreato-Biliary Surgery and Liver Transplant, BIRDEM General Hospital, Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajmal Quader","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Hepato-Pancreato-Biliary Surgery and Liver Transplant, United Hospital Limited, Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirza Shamsul","family":"Arefin","sequence":"additional","affiliation":[{"name":"Department of Hepato-Pancreato-Biliary Surgery and Liver Transplant, BIRDEM General Hospital, Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Saydul","family":"Aman","sequence":"additional","affiliation":[{"name":"Upazila Health Complex, Tongibari, Munshiganj, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmud Mohammad","family":"Sarder","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary, Pancreatic and Liver Transplant Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjida","family":"Siraj","sequence":"additional","affiliation":[{"name":"National Institute of Preventive and Social Medicine, Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-22-20260325","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/hpb.12291","article-title":"Surgical management of hepatic hemangiomas: a multi-institutional experience","volume":"16","author":"Miura,","year":"2014","journal-title":"HPB"},{"key":"R2-22-20260325","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/jhbp.464","article-title":"Proposal of size-based surgical indication criteria for liver hemangioma based on a nationwide survey in Japan","volume":"24","author":"Sakamoto,","year":"2017","journal-title":"J. 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