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The symptoms of RRD can range from mild redness to extensive dermatitis. Antineoplastic drugs such as doxorubicin, docetaxel, paclitaxel, and gemcitabine are most commonly associated with radiation recall reactions. These reactions can also occur with antibiotics and anti-tubercular drugs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 38-years-old woman with hormone receptor-negative, HER2-positive inflammatory breast cancer (right), clinical stage cT4dN1Mx, received neoadjuvant chemotherapy with AC &gt; TH protocol at 3 weeks intervals (Anthracycline-Doxorubicin plus Cyclophosphamide X 4 cycles, then docetaxel plus Trastuzumab X 4 cycles) followed by modified radical mastectomy followed by adjuvant locoregional radiotherapy. She received the 5th cycle and 6th cycle trastuzumab monotherapy just before the start of surgery and radiotherapy, respectively. After 1 month of completion of radiotherapy, during her seventh cycle of Trastuzumab monotherapy, she developed mild edema with erythematous change over the previously irradiated area with fever. A skin biopsy was taken to exclude any recurrence; however, no evidence of malignancy was found.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>We diagnosed it as a case of RRD. We managed her conservatively. Later, she was rechallenged with the same dose in subsequent cycles with systemic steroid coverage, which she tolerated very well, except for the reappearance of mild erythema following each cycle of maintenance dose of Trastuzumab.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Radiation recall dermatitis is an extremely rare phenomenon; hence, an acquaintance of clinicians with this rare entity is essential for timely diagnosis and appropriate management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.109864","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T14:11:57Z","timestamp":1717596717000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Radiation recall dermatitis in HER 2 positive breast cancer patients triggered by trastuzumab: A rare case report and review of literature"],"prefix":"10.1097","volume":"120","author":[{"given":"Jannatul","family":"Ferdause","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Ahsania Mission Cancer and General Hospital, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Ariful","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Ahsania Mission Cancer and General Hospital, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nusrat","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Ahsania Mission Cancer and General Hospital, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shafiul A.K.M.","family":"Kadir","sequence":"additional","affiliation":[{"name":"Quest Bangladesh Biomedical Research Center, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Ariful","family":"Haque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"2","key":"R1-83-20260325","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1148\/73.2.175","article-title":"Potentiation of X-ray effects by actinomycin D","volume":"73","author":"D'Angio,","year":"1959","journal-title":"Radiology"},{"issue":"11","key":"R2-83-20260325","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1634\/theoncologist.2009-0090","article-title":"Radiation recall with anticancer agents","volume":"15","author":"Burris,","year":"2010","journal-title":"Oncologist"},{"issue":"4","key":"R3-83-20260325","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.ijrobp.2021.02.048","article-title":"COVID-19 vaccine-induced radiation recall phenomenon","volume":"110","author":"Soyfer,","year":"2021","journal-title":"International Journal of Radiation Oncology*Biology*Physics"},{"issue":"7","key":"R4-83-20260325","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1016\/j.ejca.2012.12.009","article-title":"Targeted therapy-induced radiation recall","volume":"49","author":"Levy,","year":"2013","journal-title":"Eur. 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