{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T21:12:52Z","timestamp":1778188372574,"version":"3.51.4"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T00:00:00Z","timestamp":1725235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>The occurrence of ovarian tumors during pregnancy is relatively low, with an incidence of approximately 0.05 %. Both primary ovarian cancer and metastatic malignancies are uncommon in pregnant women, and there is often a delay in diagnosing these conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We report the case of rectal cancer with ovarian metastasis discovered in a 36-year-old multiparous pregnant woman who presented at 21 weeks gestation with constipation and increased abdominal volume over the past three weeks. These symptoms were associated with loss of appetite and general fatigue. Further investigations revealed a 12 \u00d7 9 cm mass on the left side of the uterus and a 5.2 \u00d7 4 \u00d7 3.6 cm mass in the recto-sigmoid region. Initially, the patient underwent left adnexectomy, peritoneal cytology, biopsies of the peritoneum, epiploic region, and right ovary. Subsequently, the pregnancy was continued until 34 weeks' amenorrhea, when the fetus was extracted, and a complete surgical procedure was performed, including total hysterectomy, right adnexectomy, resection of the recto-sigmoid tumor with appendectomy and infra-gastric omentectomy. After surgery, the patient received adjuvant chemotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>It is important to consider the possibility of malignancy during pregnancy when atypical clinical presentations occur. Gastrointestinal cancer is the most common cause of Krukenberg's tumor in pregnant women. Early diagnosis of cancer at an operable stage is essential to improve prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This clinical case highlights the rarity of Krukenberg's tumor during pregnancy and the challenges encountered in diagnosing and treating this disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110235","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T02:51:39Z","timestamp":1725331899000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Concurrent rectosigmoid cancer and Krukenberg tumor in a pregnant patient: A rare clinicopathological presentation - Case report"],"prefix":"10.1097","volume":"123","author":[{"given":"Saad","family":"Benali","sequence":"first","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelhamid","family":"Benlghazi","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza","family":"Messaoudi","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajar","family":"El Agouri","sequence":"additional","affiliation":[{"name":"Department of Pathology Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moad","family":"Belouad","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaouad","family":"Kouach","sequence":"additional","affiliation":[{"name":"Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"1","key":"R1-66-20260507","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.bpobgyn.2009.08.001","article-title":"Gynaecologic cancer complicating pregnancy: an overview","volume":"24","author":"Amant,","year":"2010","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"issue":"9","key":"R2-66-20260507","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1111\/jog.12463","article-title":"Pregnancy complicated by a K rukenberg tumor with an undetermined origin and its management","volume":"40","author":"Tulek,","year":"2014","journal-title":"J. Obstet. Gynaecol. Res."},{"issue":"5","key":"R3-66-20260507","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg."},{"key":"R5-66-20260507","first-page":"1","article-title":"Krukenberg tumor in pregnancy","volume":"15","author":"Magudapathi,","year":"2017","journal-title":"Indian J. Gynecol. Oncol."},{"issue":"5","key":"R6-66-20260507","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/uog.4020","article-title":"Imaging in gynecological disease (1): ultrasound features of metastases in the ovaries differ depending on the origin of the primary tumor","volume":"29","author":"Testa,","year":"2007","journal-title":"Ultrasound Obstet. Gynecol."},{"issue":"3","key":"R7-66-20260507","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00004728-199605000-00013","article-title":"CT and MR findings of Krukenberg tumors: comparison with primary ovarian tumors","volume":"20","author":"Kim,","year":"1996","journal-title":"J. Comput. Assist. Tomogr."},{"issue":"3","key":"R8-66-20260507","first-page":"845","article-title":"Immunohistochemical diagnosis of Krukenberg tumors","volume":"58","author":"Cr\u0103ciun,","year":"2017","journal-title":"Romanian J. Morphol. Embryol."},{"issue":"7","key":"R9-66-20260507","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1097\/MEG.0000000000000863","article-title":"Colorectal cancer diagnosed during pregnancy: systematic review and treatment pathways","volume":"29","author":"Pellino,","year":"2017","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"issue":"5","key":"R10-66-20260507","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/0002-9610(55)90705-4","article-title":"Management of primary carcinoma of the rectum diagnosed during pregnancy","volume":"90","author":"McLean,","year":"1955","journal-title":"Am. J. Surg."},{"issue":"2","key":"R11-66-20260507","doi-asserted-by":"crossref","first-page":"885","DOI":"10.21037\/jgo-21-31","article-title":"Colorectal cancer in pregnancy: a case report and literature review","volume":"12","author":"Yang,","year":"2021","journal-title":"J. Gastrointest. 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Belg."}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224010162?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224010162?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2024.110235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T21:01:20Z","timestamp":1778187680000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2024.110235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":11,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2024.110235","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-08-02","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-31","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}