{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T21:12:46Z","timestamp":1778188366907,"version":"3.51.4"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Situs inversus totalis, a rare congenital condition, is characterized by the mirror-image reversal of the abdominal and thoracic organs. Amoebic liver abscess and emphysematous gallbladder are severe gastrointestinal infections. The coexistence of these three conditions is extremely rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We present the case of a 65-year-old male who presented with abdominal pain, fever, and jaundice. Investigations revealed situs inversus totalis, amoebic liver abscess, and emphysematous gallbladder. The patient underwent successful treatment with antibiotics and open surgery drainage of the liver abscess, and subtotal cholecystectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>The co-occurrence of situs inversus totalis, amoebic liver abscess, and emphysematous gallbladder poses a diagnostic challenge and requires thorough evaluation and appropriate management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Situs inversus totalis may coincide with other conditions like amebic abscess and emphysematous gallbladder, complicating diagnosis and treatment. Early diagnosis and prompt intervention are crucial to improve outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110249","type":"journal-article","created":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T17:49:10Z","timestamp":1725817750000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A case of amoebic liver abscess and emphysematous gallbladder in a 65-year-old male with situs inversus totalis"],"prefix":"10.1097","volume":"123","author":[{"given":"Shadi","family":"Issa","sequence":"first","affiliation":[{"name":"General Surgery Department, Faculty of medicine, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousef","family":"Alsaffaf","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hama University, Hama, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Sheikh Sobeh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hama University, Hama, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suaad","family":"Hamsho","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Faculty of Medicine, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moulham","family":"Ali","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Faculty of medicine, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-78-20260507","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.2147\/IJGM.S295444","article-title":"Situs Inversus Totalis: a clinical review","volume":"15","author":"Eitler,","year":"2022","journal-title":"Int. J. Gen. Med."},{"issue":"1","key":"R2-78-20260507","article-title":"Situs inversus totalis with liver abcess","volume":"1","author":"Mufti,","year":"2009","journal-title":"Khyber Med. Univ. J."},{"key":"R3-78-20260507","first-page":"823","article-title":"Amoebic liver abscess revealing a situs inversus totalis","volume":"7","author":"B\u00e2,","year":"2016","journal-title":"Int. J. Case Rep. Images"},{"issue":"39","key":"R4-78-20260507","doi-asserted-by":"crossref","first-page":"6878","DOI":"10.14260\/jemds\/2015\/996","article-title":"A rare case report of situs inversus totalis with ruptured amoebic liver abscess in a patient suffering from serum hepatitis","volume":"4","author":"Pattnayak,","year":"2015","journal-title":"J. Evol. Med. Dent. Sci."},{"issue":"5","key":"R5-78-20260507","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg. Lond. Engl."},{"key":"R6-78-20260507","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12882-016-0237-3","article-title":"Emphysematous cholecystitis presenting as gas-forming liver abscess and pneumoperitoneum in a dialysis patient: a case report and review of the literature","volume":"17","author":"Liao,","year":"2016","journal-title":"BMC Nephrol."},{"issue":"1","key":"R7-78-20260507","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1186\/s12879-016-2093-y","article-title":"Amoebic liver abscess: an unusual cause for a right iliac fossa mass: a case report","volume":"16","author":"Ratnasamy,","year":"2016","journal-title":"BMC Infect. Dis."},{"issue":"3","key":"R8-78-20260507","first-page":"176","article-title":"ERCP and situs inversus","volume":"114","author":"Valdivielso Cort\u00e1zar,","year":"2022","journal-title":"Rev. Esp. Enferm. Dig."},{"issue":"4","key":"R9-78-20260507","doi-asserted-by":"crossref","first-page":"604","DOI":"10.3748\/wjg.v19.i4.604","article-title":"Emphysematous cholecystitis with massive gas in the abdominal cavity","volume":"19","author":"Miyahara,","year":"2013","journal-title":"World J. Gastroenterol."},{"issue":"4","key":"R10-78-20260507","first-page":"478","article-title":"A case of emphysematous cholecystitis managed by laparoscopic surgery","volume":"9","author":"Bouras,","year":"2005","journal-title":"JSLS"},{"issue":"10","key":"R11-78-20260507","article-title":"Overcoming anatomical challenges: laparoscopic cholecystectomy in situs Inversus Totalis","volume":"15","author":"Meza-Martinez,","year":"2023","journal-title":"Cureus"},{"issue":"3","key":"R12-78-20260507","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/cld.1128","article-title":"Liver abscess: complications and treatment","volume":"18","author":"Sharma,","year":"2021","journal-title":"Clin. Liver. Dis. (Hoboken)"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224010307?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224010307?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2024.110249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T21:00:29Z","timestamp":1778187629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2024.110249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":12,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2024.110249","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-07-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}