{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:08:50Z","timestamp":1786118930638,"version":"build-2736575974"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T00:00:00Z","timestamp":1726531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Small cell neuroendocrine carcinoma is a rare and aggressive pathology with significant diagnostic challenges. Treatment typically involves multimodal therapy, including surgery and chemotherapy, but outcomes vary. The objective of this study is to describe and report a case of small cell neuroendocrine carcinoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A case study illustrates the follow-up of a 36-year-old female patient from diagnostic biopsy to maxillectomy, followed by adjuvant chemotherapy with cisplatin and etoposide. Small cell neuroendocrine carcinoma poses significant challenges due to its rarity and aggressive behavior.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Multimodal therapy remains the mainstay, but the prognosis is unfavorable. Despite advances, managing small cell neuroendocrine carcinoma remains challenging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Integrated approaches are crucial, underscoring the need for ongoing research to improve outcomes in this rare malignancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110321","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T21:23:18Z","timestamp":1726780998000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Small cell neuroendocrine carcinoma in maxillary sinus: a case report and literature review"],"prefix":"10.1097","volume":"124","author":[{"given":"Hugo Humberto","family":"Romero Alvarenga","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery of \u201cHospital Escuela Universitario de Honduras\u201d, Honduras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Jos\u00e9","family":"Guifarro","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery of \u201cHospital Escuela Universitario de Honduras\u201d, Honduras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"D\u00edaz","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery of \u201cHospital Escuela Universitario de Honduras\u201d, Honduras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agatha","family":"Reyes","sequence":"additional","affiliation":[{"name":"Medical Oncologist at the Hemato-Oncology Unit of the Roosevelt Hospital, Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Luis","family":"Piedra Burneo","sequence":"additional","affiliation":[{"name":"Postgraduate degree in oral and maxillofacial surgery, National Autonomous University of Mexico, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20260421","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1017\/S0022215100063660","article-title":"Oat cell carcinoma and paranasal sinuses","volume":"79","author":"Chowdhuri,","year":"1965","journal-title":"J. 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