{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:08:54Z","timestamp":1786118934388,"version":"build-2736575974"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T00:00:00Z","timestamp":1727568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"ABSTRACT<\/jats:title>\n \n Introduction and importance:<\/jats:title>\n Chronic appendicitis in pediatric patients is rare and challenging to diagnose, typically leading to surgical resection. However, Endoscopic Retrograde Appendicitis Therapy (ERAT) offers a minimally invasive alternative that preserves the appendix, maintaining its immune and digestive functions.<\/jats:p>\n <\/jats:sec>\n \n Case presentation:<\/jats:title>\n A 13-year-old boy with a year-long history of worsening abdominal pain underwent ERAT. The procedure provided symptom relief and preserved the appendix.<\/jats:p>\n <\/jats:sec>\n \n Clinical discussion:<\/jats:title>\n ERAT successfully treated the appendicitis while preserving the appendix, which plays crucial immune and digestive roles, especially in children.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n ERAT is a promising, non-surgical alternative for chronic appendicitis in pediatric patients, warranting further study.<\/jats:p>\n <\/jats:sec>\n \n Highlights<\/jats:title>\n <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110386","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T11:49:41Z","timestamp":1727869781000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Pediatric chronic appendicitis without surgical resection: A case study of endoscopic retrograde appendicitis therapy (ERAT)"],"prefix":"10.1097","volume":"124","author":[{"given":"Xue-Qi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of General Surgery, Children's Hospital Capital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Huan","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Children's Hospital Capital Institute of Pediatrics, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-69-20260421","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.jtbi.2007.08.032","article-title":"Biofilms in the large bowel suggest an apparent function of the human vermiform appendix","volume":"249","author":"Bollinger,","year":"2007","journal-title":"J. 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