{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:07:53Z","timestamp":1786118873511,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T00:00:00Z","timestamp":1727568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"ABSTRACT<\/jats:title>\n \n Introduction:<\/jats:title>\n \n Lower limb postural deformities are usually bilateral and in the majority of cases tend to spontaneous correction without any treatment. On the contrary, unilateral\n genu valgum<\/jats:italic>\n is a rare deformity in children, it is frequently associated with systemic pathological conditions and require a specific treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Presentation of case:<\/jats:title>\n \n A three-year-old child affected by severe unilateral left\n genu valgum<\/jats:italic>\n was followed by a multidisciplinary team. The initial treatment was medical, based on 10,000 IU of cholecalciferol every 2 months without any improvement after 6 months. Therefore, the patient was surgically treated by hemiepiphysiodesis of distal femur and proximal tibia with eight-plate obtaining a complete correction of the deformity in 10 months. Medical treatment continued for 4 years since the diagnosis. At follow-up, 18 years later, an excellent clinical result was observed.\n <\/jats:p>\n <\/jats:sec>\n \n Discussion:<\/jats:title>\n \n The association between unilateral\n genu valgum<\/jats:italic>\n and vitamin D deficiency is extremely rare. In case of unilateral limb deformity, it is essential to investigate the aetiology to obtain a correct diagnosis and perform a specific multidisciplinary treatment. The goal of the management is to correct the deformity and avoid any recurrence.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n We believe that in unilateral genu valgum is always necessary a correct multidisciplinary diagnosis and treatment. The peculiarity of our case is the long-term follow-up and the absence of recurrence despite early surgical treatment. Further studies are necessary to better define the correlation between unilateral axial deformity and vitamin D deficiency.<\/jats:p>\n <\/jats:sec>\n \n Highlights<\/jats:title>\n <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110392","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T02:30:24Z","timestamp":1727663424000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Unilateral genu valgum associated to vitamin D deficiency: A multidisciplinary approach in a patient followed from 3 to 21 years - A case report"],"prefix":"10.1097","volume":"125","author":[{"given":"S.","family":"Salera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Luciano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"De Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Rovere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"De Maio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Farsetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"2","key":"R1-5-20260423","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2106\/00004623-197557020-00021","article-title":"The development of the tibiofemoral angle in children","volume":"57","author":"Salenius,","year":"1975","journal-title":"J. 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