{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T15:08:04Z","timestamp":1776784084191,"version":"3.51.2"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T00:00:00Z","timestamp":1728864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Ectopic pancreatic tissue (EPT), also known as Heterotopic pancreas (HP), is a rare congenital anomaly characterized by the presence of pancreatic tissue outside the primary organ. This report presents a case of EPT incidentally discovered in the submucosal area of the small intestine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 56-year-old male presented to the emergency department following a high-speed car collision, reporting abdominal pain after impact with the steering wheel. Physical examination revealed left upper quadrant tenderness. Imaging studies showed free fluid in the abdominal and pelvic cavities, mesenteric damage, and increased intestinal wall thickness. Surgical exploration confirmed hemoperitoneum and a non-viable 30 cm segment of the small intestine, which was resected. Subsequent pathological examination revealed a 1.5 cm submucosal mass, diagnosed as EPT. The patient recovered uneventfully and was discharged in stable condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Clinically significant lesions are typically larger than 1.5 cm and involve the mucosa, with pain as the most common symptom. They can also cause severe complications such as intestinal obstruction, perforation, peritonitis, and gastrointestinal bleeding. Additionally, EPT can be associated with malignant transformations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>While often asymptomatic, EPT can lead to significant complications, making surgical resection essential for both symptomatic and incidental cases, particularly since diagnosis is frequently established postoperatively through histological examination. Although trauma may not directly cause EPT, its management in emergency settings can facilitate evaluations that reveal lesions capable of causing severe complications if left undiagnosed. Given the diverse symptoms associated with this condition, EPT should be considered in the differential diagnosis of intestinal lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110461","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T04:33:41Z","timestamp":1729053221000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Ectopic pancreatic tissue in the small intestine: An uncommon finding following trauma"],"prefix":"10.1097","volume":"124","author":[{"given":"Paridokht","family":"Karimian","sequence":"first","affiliation":[{"name":"Pathology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahand","family":"Karimzadhagh","sequence":"additional","affiliation":[{"name":"Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bita","family":"Amirian","sequence":"additional","affiliation":[{"name":"School of Medicine, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azita","family":"Rafiee","sequence":"additional","affiliation":[{"name":"Pathologist, Iranian Medical and Pathology Laboratory, Zahedan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leila","family":"Shokrgozar","sequence":"additional","affiliation":[{"name":"General Surgery, Faculty of Medicine, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nooshin","family":"Zaresharifi","sequence":"additional","affiliation":[{"name":"Pathology, Trauma Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"2","key":"R1-138-20260421","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1053\/j.gastro.2006.12.054","article-title":"Pancreatic development and disease","volume":"132","author":"Cano,","year":"2007","journal-title":"Gastroenterology"},{"issue":"2","key":"R2-138-20260421","doi-asserted-by":"crossref","first-page":"180","DOI":"10.30699\/ijp.14.2.180","article-title":"Heterotopic pancreas as a leading point of intussusception: a case report","volume":"14","author":"Saffar,","year":"2019","journal-title":"Iran. 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Case Rep."},{"issue":"1","key":"R6-138-20260421","doi-asserted-by":"crossref","DOI":"10.1186\/s40064-015-1072-x","article-title":"Clinical picture: multiple sites of ectopic pancreatic tissue","volume":"4","author":"Straatman,","year":"2015","journal-title":"SpringerPlus"},{"issue":"45","key":"R7-138-20260421","doi-asserted-by":"crossref","first-page":"6098","DOI":"10.3748\/wjg.v13.i45.6098","article-title":"Heterotopic pancreas in the stomach: a case report and literature review","volume":"13","author":"Christodoulidis,","year":"2007","journal-title":"World J. Gastroenterol."},{"issue":"3","key":"R8-138-20260421","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1159\/000526135","article-title":"Heterotopic pancreas in the duodenum diagnosed after laparoscopic biopsy","volume":"16","author":"Pham,","year":"2022","journal-title":"Case Rep. 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