{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:08:18Z","timestamp":1786118898131,"version":"build-2736575974"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Bone hydatidosis is a rare manifestation of Echinococcus infection, presenting significant diagnostic and therapeutic challenges. This case report describes the successful management of an extensive hydatid disease involving the entire humerus and scapula.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 44-year-old male presented with progressive right arm pain and swelling. Imaging studies revealed extensive hydatid cysts throughout the humerus and scapula. Positive ELISA confirmed the diagnosis for anti-Echinococcus antibodies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Treatment involved a multidisciplinary approach. The patient received preoperative Albendazole for six weeks. The surgical intervention included total humerus endoprosthesis replacement and extended curettage of the scapula. Intraoperative scolicidal agent (povidone-iodine) was used. Postoperative anthelmintic therapy was administered for three months. At five-year follow-up, the patient remained disease-free with satisfactory upper limb function. No recurrence was observed, although the patient declined further corrective surgery for prosthetic subluxation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights the efficacy of a comprehensive approach to extensive bone hydatidosis, combining wide resection, prosthetic reconstruction, and perioperative anthelmintic therapy. The successful outcome supports the use of total bone endoprosthesis in suitable cases of extensive long-bone hydatidosis. Long-term follow-up is crucial due to the risk of recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110503","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T12:00:25Z","timestamp":1729684825000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Extensive humerus and scapula hydatidosis: A unique case report and comprehensive review of management strategies"],"prefix":"10.1097","volume":"125","author":[{"given":"Sadegh","family":"Saberi","sequence":"first","affiliation":[{"name":"Joint Reconstruction Research Center, Department of Orthopedics, Tehran University of Medical Sciences, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamed","family":"Naghizadeh","sequence":"additional","affiliation":[{"name":"Joint Reconstruction Research Center, Department of Orthopedics, Tehran University of Medical Sciences, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nima","family":"Bagheri","sequence":"additional","affiliation":[{"name":"Joint Reconstruction Research Center, Department of Orthopedics, Tehran University of Medical Sciences, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Saffar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Cancer Institute, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeinab Mohseni","family":"Afshar","sequence":"additional","affiliation":[{"name":"Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyyed Saeed","family":"Khabiri","sequence":"additional","affiliation":[{"name":"Joint Reconstruction Research Center, Department of Orthopedics, Tehran University of Medical Sciences, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-28-20260423","first-page":"101","volume":"8","author":"Kizilkaya,","year":"2002","journal-title":"Hepatic, extrahepatic soft tissue and bone involvement in hydatid disease"},{"key":"R3-28-20260423","first-page":"1","volume":"1","author":"Ebrahimi,","year":"2007","journal-title":"Whole body bone scintigraphy in osseous hydatosis: a case report"},{"issue":"1","key":"R4-28-20260423","first-page":"75","article-title":"Mondher Mestiri MJWjos","volume":"25","author":"Mongi Zlitni,","year":"2001","journal-title":"Hydatid cyst of bone: diagnosis and treatment"},{"issue":"3","key":"R5-28-20260423","first-page":"442","volume":"33","author":"Babitha,","year":"2015","journal-title":"Hydatid cyst of bone"},{"issue":"9","key":"R6-28-20260423","volume":"7","author":"Neumayr,","year":"2013","journal-title":"Spinal cystic echinococcosis-a systematic analysis and review of the literature: part 2. Treatment, follow-up and outcome"},{"issue":"5","key":"R7-28-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg."},{"issue":"10","key":"R8-28-20260423","first-page":"1326","volume":"10","author":"Barth,","year":"2021","journal-title":"Morphological characteristics of alveolar and cystic echinococcosis lesions in human liver and bone"},{"issue":"2","key":"R9-28-20260423","first-page":"475","volume":"23","author":"Polat,","year":"2003","journal-title":"Hydatid disease from head to toe"},{"issue":"3","key":"R10-28-20260423","first-page":"617","volume":"100","author":"Cattaneo,","year":"2019","journal-title":"Cystic echinococcosis of the bone: a European multicenter study"},{"issue":"9","key":"R11-28-20260423","first-page":"1","article-title":"Mahera HJJATJoA, Surgery R","volume":"18","author":"Vallianatos,","year":"2002","journal-title":"Echinococcal synovitis of the knee joint"},{"issue":"2","key":"R12-28-20260423","first-page":"163","volume":"17","author":"Battyany,","year":"2011","journal-title":"Subcutaneous hydatid cyst in the popliteal fossa at the site of a previous wasp sting."},{"issue":"2","key":"R13-28-20260423","first-page":"216","article-title":"Shetty NRJJoNS","volume":"91","author":"Bhojraj,","year":"1999","journal-title":"Primary hydatid disease of the spine: an unusual cause of progressive paraplegia: case report and review of literature"},{"issue":"11","key":"R14-28-20260423","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1007\/s003300000771","article-title":"Multiple, primary spinal-paraspinal hydatid cysts","volume":"11","author":"Sener,","year":"2001","journal-title":"Eur. Radiol."},{"issue":"982","key":"R16-28-20260423","first-page":"536","article-title":"Wen HJPmj","volume":"83","author":"Song,","year":"2007","journal-title":"Bone hydatid disease"},{"key":"R18-28-20260423","article-title":"Hwaij FJIJoSCR","volume":"102","author":"Alasaad,","year":"2023","journal-title":"Case report: hydatid cyst of bone in the distal femur with untypical presentation treated surgically"},{"key":"R19-28-20260423","first-page":"57","article-title":"Song XJIJoID","volume":"18","author":"Liang,","year":"2014","journal-title":"Treatment experiences of pelvic bone hydatidosis"},{"issue":"2","key":"R20-28-20260423","first-page":"103","article-title":"Khandelwal NJTp","volume":"6","author":"Mehta,","year":"2016","journal-title":"Radiological manifestations of hydatid disease and its complications"},{"issue":"1","key":"R21-28-20260423","first-page":"18","article-title":"Liu WJRoID","volume":"9","author":"Guo,","year":"2022","journal-title":"Hydatid disease of bone: Imaging features"},{"issue":"1","key":"R22-28-20260423","first-page":"89","volume":"69","author":"Sapkas,","year":"1998","journal-title":"Hydatid disease of bones and joints: 8 cases followed for 4-16 years"},{"issue":"5","key":"R23-28-20260423","first-page":"447","article-title":"Non-spinal hydatid disease of bone: a series of nine cases","volume":"10","author":"Jamshidi,","year":"2022","journal-title":"The archives of bone and joint surgery"},{"issue":"2","key":"R24-28-20260423","doi-asserted-by":"crossref","first-page":"435","DOI":"10.52312\/jdrs.2022.644","article-title":"A rare lesion that mimics a bone tumor: osseous hydatidosis","volume":"33","author":"Atalay,","year":"2022","journal-title":"Joint Diseases and Related Surgery"},{"issue":"7","key":"R25-28-20260423","first-page":"1005","article-title":"Saglik YJTJoB, volume JSB","volume":"83","author":"Yildiz,","year":"2001","journal-title":"The use of polymethylmethacrylate in the management of hydatid disease of bone."},{"issue":"4","key":"R26-28-20260423","first-page":"25","article-title":"Pelvic hydatid disease: a case report and review of literature","volume":"7","author":"Bhatnagar,","year":"2017","journal-title":"Journal of Orthopaedic Case Reports."},{"key":"R27-28-20260423","first-page":"234","article-title":"Research\u00ae R","volume":"432","author":"Arazi,","year":"2005","journal-title":"Primary echinococcus infestation of the bone and muscles."},{"issue":"6","key":"R28-28-20260423","first-page":"448","volume":"6","author":"Arif,","year":"2008","journal-title":"Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver."},{"issue":"3","key":"R29-28-20260423","first-page":"821","volume":"69","author":"Steinmetz,","year":"2014","journal-title":"Treatment challenges associated with bone echinococcosis."},{"issue":"5","key":"R30-28-20260423","first-page":"440","volume":"66","author":"Wirbel,","year":"1995","journal-title":"Hydatid disease of the pelvis and the femur: a case report."},{"issue":"4","key":"R31-28-20260423","first-page":"287","article-title":"Grimer RJAotRCoSoE","volume":"82","author":"Metcalfe,","year":"2000","journal-title":"Tackling osseous hydatidosis using orthopaedic oncology techniques."},{"key":"R32-28-20260423","article-title":"Two cases of femoral hydatidosis secondary to canine tapeworm treated by albendazole and prosthetic reconstruction.","volume":"2013","author":"Lesl\u00e9","year":"2013"},{"issue":"1","key":"R33-28-20260423","volume":"5","author":"Moore,","year":"2015","journal-title":"Hydatid disease of the femur treated with a total femoral replacement: a case report."},{"key":"R34-28-20260423","first-page":"296","article-title":"Hydatidosis of the complete humerus. Treated with radical resection and endoprosthesis","volume":"65","author":"Patino,","year":"2019","journal-title":"Case Report."},{"issue":"3","key":"R35-28-20260423","first-page":"262","article-title":"Pr\u00f3tesis total de f\u00e9mur en un paciente con quiste \u00f3seo hidat\u00eddico complicado","volume":"85","author":"Minoru Isobe,","year":"2020","journal-title":"Reporte de un Caso."},{"issue":"4","key":"R36-28-20260423","volume":"11","author":"Lal,","year":"2021","journal-title":"Total femoral replacement for complicated echinococcus infection: sixteen-year follow-up."},{"issue":"2","key":"R38-28-20260423","first-page":"115","article-title":"Safioleas MJPi","volume":"58","author":"Stamatakos,","year":"2009","journal-title":"Anthelminthic treatment: an adjuvant therapeutic strategy against Echinococcus granulosus"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224012847?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224012847?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2024.110503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:59:45Z","timestamp":1786035585000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2024.110503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":34,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2024.110503","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-09-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}