{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T21:41:37Z","timestamp":1776980497551,"version":"3.51.4"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and Importance:<\/jats:title>\n                    <jats:p>Urachal carcinoma (UrC) is a rare bladder malignancy originating from the urachus. Comprising around 90 % adenocarcinomas, most cases are invasive. Urachal adenocarcinoma is less common than its non-urachal counterpart and is recognized for its aggressive nature, often diagnosed at advanced stages with a poor prognosis. Early stages typically present as asymptomatic, making timely diagnosis challenging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>We present the case of a 58-year-old female who exhibited painless hematuria, leading to further investigation. The definitive diagnosis of invasive mucinous urachal adenocarcinoma was established through cystoscopy and transurethral resection of bladder tumor (TURBT). Surgical intervention was undertaken to manage the condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Discussion:<\/jats:title>\n                    <jats:p>The gold standard treatment for muscle-invasive UrC is radical cystectomy. This case underscores the importance of recognizing urinary symptoms and utilizing appropriate diagnostic procedures to identify this rare malignancy early. The surgical approach is crucial in improving patient outcomes, especially in advanced cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Invasive mucinous urachal adenocarcinoma is a rare but aggressive cancer that requires prompt diagnosis and intervention. Surgical management proved effective in this case, emphasizing the need for awareness and regular follow-up in patients to monitor for recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110524","type":"journal-article","created":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T05:41:07Z","timestamp":1730094067000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Invasive mucinous urachal adenocarcinoma: A case report of surgical management and insights from the literature"],"prefix":"10.1097","volume":"125","author":[{"given":"Manar Shukri","family":"Jaber","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Polytechnic University of Palestine, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sondos","family":"Mojahed","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Polytechnic University of Palestine, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bayan Abu","family":"Rajab","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Polytechnic University of Palestine, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahaf Yousef","family":"Shalodi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Polytechnic University of Palestine, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil N.M.","family":"Abuzaina","sequence":"additional","affiliation":[{"name":"Hebron University, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamal Ata","family":"Jaber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-47-20260423","doi-asserted-by":"crossref","DOI":"10.1016\/j.tria.2019.100041","article-title":"Urachal anomalies: a review of pathological conditions, diagnosis, and management","volume":"16","author":"Wilson,","year":"2019","journal-title":"Translational Research in Anatomy."},{"issue":"2","key":"R2-47-20260423","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.juro.2008.05.039","article-title":"Urachal adenocarcinoma","volume":"180","author":"Paras,","year":"2008","journal-title":"J. Urol."},{"issue":"3","key":"R3-47-20260423","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.21037\/tau-19-863","article-title":"U-shaped relationship of age at diagnosis and cancer-specific mortality in primary urachal adenocarcinoma: a cohort study","volume":"9","author":"Yu,","year":"2020","journal-title":"Transl Androl Urol."},{"issue":"1","key":"R4-47-20260423","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-5347(17)50167-6","article-title":"Malignant urachal lesions","volume":"131","author":"Sheldon,","year":"1984","journal-title":"J. Urol."},{"issue":"Pt 2","key":"R5-47-20260423","first-page":"170","article-title":"The Urachus: its anatomy, histology and development","volume":"64","author":"Begg,","year":"1930","journal-title":"J. Anat."},{"issue":"2","key":"R6-47-20260423","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1148\/radiographics.21.2.g01mr02451","article-title":"Urachal remnant diseases: spectrum of CT and US findings","volume":"21","author":"Yu,","year":"2001","journal-title":"Radiographics"},{"issue":"8","key":"R7-47-20260423","article-title":"Urachal carcinoma, an unusual possibility of hematuria","volume":"12","author":"Tiutiuc\u0103,","year":"2022","journal-title":"Case Report and Literature Review. Diagnostics (Basel)."},{"issue":"1","key":"R8-47-20260423","doi-asserted-by":"crossref","DOI":"10.4103\/jcrt.JCRT_28_20","article-title":"Urachal adenocarcinoma: a case report and review of the literature","volume":"18","author":"G\u00fcral,","year":"2022","journal-title":"J. Cancer Res. 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