{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T06:33:29Z","timestamp":1778049209714,"version":"3.51.4"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T00:00:00Z","timestamp":1729814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Biliary ascariasis is a rare complication of Ascaris lumbricoides infestation, often leading to biliary obstruction and cholangitis. Gallbladder perforation secondary to biliary ascariasis is exceedingly uncommon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 28-year-old female farmer from a rural area presented with a one-year history of intermittent right upper quadrant pain, worsened by fatty meals. Her symptoms progressed a week before presentation to include fever, jaundice, dark urine, and pruritus. Examination revealed a positive Murphy sign and jaundice, with laboratory results showing leukocytosis and elevated bilirubin. Imaging confirmed biliary ascariasis with choledocholithiasis and ascending cholangitis. Intraoperatively, a sealed perforation of the gallbladder was found alongside a dead Ascaris and multiple stones in the common bile duct (CBD). Surgical intervention included removal of the worms and stones, cholecystectomy and CBD irrigation. Postoperative recovery was uneventful, and the patient was discharged with antihelminthic therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Biliary ascariasis is an infrequent cause of biliary obstruction but can lead to severe complications such as cholangitis and gallbladder perforation. Diagnosis is often clinical, supported by ultrasound and CT imaging. Management involves both medical and surgical approaches, including antibiotics and surgical removal of worms and stones. This case represents a type II gallbladder perforation, as per the Neimeier classification, where an abscess is contained by adhesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights the importance of recognizing parasitic infections as a potential cause of severe biliary complications, particularly in endemic regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110536","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T03:50:31Z","timestamp":1730260231000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Gallbladder perforation due to biliary ascariasis: A case report"],"prefix":"10.1097","volume":"125","author":[{"given":"Abel Girma","family":"Demessie","sequence":"first","affiliation":[{"name":"Department of Surgery, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suleiman","family":"Ayalew","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Negussie","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masresha","family":"Bereket G. Mariam","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leaynadis Kassa","family":"Lake","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheru Lilay","family":"Gebrehiwet","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"4","key":"R2-59-20260423","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.jamcollsurg.2008.05.020","article-title":"Ascariasis in the hepatobiliary system: laparoscopic management","volume":"207","author":"Astudillo,","year":"2008","journal-title":"J. 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