{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:07:56Z","timestamp":1786118876435,"version":"build-2736575974"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T00:00:00Z","timestamp":1731110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Neurofibromatosis type 1 (NF1) affects the musculoskeletal system as well as the cervical spine. It is associated with severe, progressive cervical kyphosis. Surgical intervention is the treatment of choice to avoid neurological impairment and malalignment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We herein report an 11-year-old NF-1 patient with severe cervical kyphosis and intact neurological status. We applied five days of cervical traction followed by surgery utilizing the combined cervical approach (posterior release, anterior corpectomy and reconstruction, and posterior cervicothoracic instrumentation). In one-year follow-up, atlantoaxial dislocation (AAD) and basilar invagination (BI) were detected in neuroimagings. The complication was corrected by adding C1 to the previous construct via unilateral C1 lateral mass screw, contralateral C1 sublaminar hook, unilateral C3 and contralateral C4 sublaminar hook insertion, fixed with contoured rods medial to previous rods. This led to the correction of the AAD and the BI and the patients remained neurologically intact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Severe cervical kyphosis in the setting of NF-1 is progressive and carries a considerable risk of neurologic compromise. Surgical intervention is thus necessary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The combined approach with complete spinal column reconstruction is the surgical approach of choice. However, complete curve correction to near-normal lordosis carries the risk of proximal junctional failure (PJF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110599","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T21:19:15Z","timestamp":1731705555000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Basilar invagination and atlantoaxial dislocation as a complication of severe dystrophic cervical kyphosis correction in neurofibromatosis type 1: Report of a rare case and review of literature"],"prefix":"10.1097","volume":"125","author":[{"given":"Seyed Reza","family":"Mousavi","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid Reza","family":"Farrokhi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyvan","family":"Eghbal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammadhadi Amir Shahpari","family":"Motlagh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Jangiaghdam","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fariborz","family":"Ghaffarpasand","sequence":"additional","affiliation":[{"name":"Research Center for Neuromodulation and Pain, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"9","key":"R1-119-20260423","doi-asserted-by":"crossref","DOI":"10.3390\/genes10090675","article-title":"Prevalence, type, and molecular spectrum of NF1 mutations in patients with neuro- fibromatosis type 1 and congenital heart disease","volume":"10","author":"Pinna,","year":"2019","journal-title":"Genes (Basel)"},{"key":"R2-119-20260423","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jocn.2020.05.014","article-title":"Clinical and neuroradiological characterisation of spinal lesions in adults with neurofibromatosis type 1","volume":"77","author":"Curtis-Lopez,","year":"2020","journal-title":"J. Clin. Neurosci."},{"issue":"5","key":"R3-119-20260423","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00586-004-0829-7","article-title":"Spinal deformity in neurofibromatosis type-1: diagnosis and treatment","volume":"14","author":"Tsirikos,","year":"2005","journal-title":"Eur. Spine J."},{"issue":"2","key":"R4-119-20260423","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4103\/joasis.joasis_15_20","article-title":"Spinal deformities in neurofibromatosis 1","volume":"17","author":"Pillai,","year":"2020","journal-title":"J. Orthop. Assoc. South Indian States"},{"issue":"4","key":"R5-119-20260423","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.spinee.2013.06.059","article-title":"Factors determining cervical spine sagittal balance in asymptomatic adults: correlation with spinopelvic balance and thoracic inlet alignment","volume":"15","author":"Lee,","year":"2015","journal-title":"Spine J."},{"issue":"3","key":"R6-119-20260423","doi-asserted-by":"crossref","first-page":"422","DOI":"10.21037\/jss-21-54","article-title":"Etiology and treatment of cervical kyphosis: state of the art review-a narrative review","volume":"7","author":"Ogura,","year":"2021","journal-title":"J. Spine Surg."},{"issue":"4","key":"R7-119-20260423","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmg.2019.103815","article-title":"Severe thoracic and spinal bone abnormalities in neurofibromatosis type 1","volume":"63","author":"Prudhomme,","year":"2020","journal-title":"Eur. J. Med. 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Neurosurg. Spine"},{"issue":"1","key":"R18-119-20260423","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jspd.2012.04.004","article-title":"Neurofibromatosis: etiology, commonly encountered spinal deformities, common complications and pitfalls of surgical treatment","volume":"1","author":"Crawford,","year":"2012","journal-title":"Spine Deform."},{"key":"R19-119-20260423","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.wneu.2020.07.176","article-title":"Atlantoaxial dislocation associated with type 1 neurofibromatosis: case report and review of the literature","volume":"143","author":"Ding,","year":"2020","journal-title":"World Neurosurg."},{"issue":"5","key":"R20-119-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg. Lond. 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Disord."},{"key":"R28-119-20260423","article-title":"Posterior-only approach for treatment of irreducible traumatic Atlanto-axial dislocation, secondary to type-II odontoid fracture; report of a missed case, its manage- ment and review of literature","volume":"114","author":"Mousavi,","year":"2023","journal-title":"Int. J. Surg. Case Rep."},{"key":"R29-119-20260423","article-title":"Reconstruction of C1 lateral mass with an expandable cage in addition to vertebral artery preservation: presenting two cases","volume":"1-6","author":"Mousavi,","year":"2021","journal-title":"Br. J. Neurosurg."},{"issue":"3","key":"R30-119-20260423","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s43390-021-00465-6","article-title":"Surgical challenges and functional outcomes in dystrophic cervical kyphosis in neurofibromatosis-1: an institutional experience","volume":"10","author":"Murlidharan,","year":"2022","journal-title":"Spine Deform."},{"issue":"0","key":"R31-119-20260423","doi-asserted-by":"crossref","first-page":"2","DOI":"10.32598\/irjns.9.2","article-title":"Launching the DCER (distraction, compression, extension, and reduction) technique in basilar invagination and atlantoaxial dislocation: a preliminary report of two cases in Iran","volume":"9","author":"Mousavi,","year":"2023","journal-title":"Iran. J. Neurosurg."},{"issue":"2","key":"R32-119-20260423","doi-asserted-by":"crossref","first-page":"194","DOI":"10.2106\/00004623-200102000-00006","article-title":"Diagnosing basilar invagination in the rheumatoid patient: the reliability of radiographic criteria","volume":"83","author":"Riew,","year":"2001","journal-title":"JBJS"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224013804?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224013804?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2024.110599","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:59:40Z","timestamp":1786035580000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2024.110599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":32,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2024.110599","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-05-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}