{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:07:50Z","timestamp":1786118870090,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Chondroid syringoma also referred to as a mixed tumor, is a benign and rare tumor originating from apocrine or eccrine sweat glands; it predominantly affects middle-aged men. While fine-needle aspiration cytology can aid in diagnosis, histological confirmation remains essential due to the potential for misdiagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A-22-year-old male who presented with a solitary, slow-growing, painless, erythematous nodule on the right nasal wing that had been present for 1 year, which was misdiagnosed as an epidermal cyst. an excisional biopsy was performed and showed in histological examination foci of myxoid to cartilaginous lakes associated with glandular structures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Chondroid syringoma characterized by mesenchymal and epithelial components. Typically presenting as a painless nodule on the head and neck, CS can be misdiagnosed due to overlapping features with other lesions. Diagnosis involves fine-needle aspiration cytology and histological confirmation. The primary treatment is surgical excision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Chondroid syringoma has distinctive histological characteristics, which include myxoid to cartilaginous components alongside glandular structures, these features are essential for accurate differentiation from other neoplasms. Surgical excision with an adequate margin of normal tissue is the recommended treatment approach to ensure complete removal and minimize recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110618","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T05:14:03Z","timestamp":1731993243000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Chondroid syringoma on the nasal wing: A case report in a 22-year-old male"],"prefix":"10.1097","volume":"125","author":[{"given":"Bakri","family":"Roumi Jamal","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Aleppo, Aleppo, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lana","family":"Sabbagh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Aleppo, Aleppo, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Asfari","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Aleppo, Aleppo, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Khayat","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Aleppo, Aleppo, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa","family":"Alzakri","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, University of Aleppo, Aleppo, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silva","family":"Ishkhanian","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, University of Aleppo, Aleppo, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"12","key":"R1-136-20260423","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1136\/bcr-2021-245354","article-title":"Isolated eyelid chondroid syringoma: a study of two cases","volume":"14","author":"Walvekar,","year":"2021","journal-title":"BMJ Case Rep."},{"issue":"1","key":"R2-136-20260423","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/ASW.0000000000000076","article-title":"Chondroid syringoma on the tip of the nose: a case report","volume":"37","author":"Halder,","year":"2024","journal-title":"Adv. Skin Wound Care"},{"issue":"2","key":"R3-136-20260423","first-page":"1","article-title":"Benign chondroid syringoma on chin: a case report and literature review","volume":"15","author":"Anandani,","year":"2023","journal-title":"Cureus"},{"issue":"2","key":"R4-136-20260423","first-page":"2","article-title":"Chondroid syringoma","volume":"49","author":"Agrawal,","year":"2008","journal-title":"Singapore Med. J."},{"issue":"1","key":"R5-136-20260423","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1177\/1203475418791558","article-title":"A case report of chondroid syringoma on the nose in a young male of middle eastern descent","volume":"23","author":"Rogalski,","year":"2019","journal-title":"J. Cutan. Med. Surg."},{"key":"R6-136-20260423","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijscr.2024.109248","article-title":"Chondroid syringoma of the nose: a rare case report and literature review","volume":"115","author":"AlSaidan,","year":"2024","journal-title":"Int. J. Surg. 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Cytopathol."},{"issue":"7","key":"R9-136-20260423","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1136\/bcr-2019-232943","article-title":"Chondroid syringoma: an unusual presentation in a 7-year-old boy","volume":"14","author":"Purkayastha,","year":"2021","journal-title":"BMJ Case Rep."}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224013993?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261224013993?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2024.110618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:59:55Z","timestamp":1786035595000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2024.110618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":9,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2024.110618","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-10-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}