{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:12:22Z","timestamp":1778278342660,"version":"3.51.4"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Schwannomas arise from Schwann cells, which make up the neural sheath of peripheral nerves. These tumors are usually seen in the head, neck and flexor surfaces, but can arise in the retroperitoneal space on rare occasions. This case gives the unique opportunity to watch the long term progression and speed of growth of this rare tumor and the development of symptoms over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Here, we describe the interesting case of a retroperitoneal Schwannoma discovered incidentally that was then monitored over the course of six years. After the tumor grew from 2.4 \u00d7 2.2 cm to 5.4 \u00d7 5.2 cm over this time, symptoms such as abdominal pain, nausea, constipation, increased urinary frequency, and left leg paresthesia arose, prompting for removal of the tumor. On follow-up two weeks later, the patient reported resolution of symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Treatment for this tumor is either immediate excision or the \u201cwatch and wait\u201d method, as this tumor has a low rate of malignant transformation. The tumor discussed in this case had a higher rate of growth before removal when compared to other studies examining retroperitoneal Schwannoma development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The \u201cwatch and wait\u201d method of treatment for this benign tumor is effective, but it is important to ensure the patient is aware that the tumor will likely continue to grow. Given this, the patient should be informed of possible mass effect symptoms to monitor for.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110622","type":"journal-article","created":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T09:35:23Z","timestamp":1731749723000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Six year natural progression of a clinically monitored retroperitoneal schwannoma: A case report"],"prefix":"10.1097","volume":"126","author":[{"given":"Elizabeth","family":"Kruse","sequence":"first","affiliation":[{"name":"University of Missouri- Kansas City School of Medicine, Kansas City, MO 64108, United States of America"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allye","family":"Gardner","sequence":"additional","affiliation":[{"name":"University of Missouri- Kansas City School of Medicine, Kansas City, MO 64108, United States of America"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Vaca","sequence":"additional","affiliation":[{"name":"University of Missouri- Kansas City School of Medicine, Kansas City, MO 64108, United States of America"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"McNally","sequence":"additional","affiliation":[{"name":"Department of Surgery, St. Luke's Health System, Kansas City, MO 64108, United States of America"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"4","key":"R1-9-20260508","doi-asserted-by":"crossref","DOI":"10.1002\/ccr3.5726","article-title":"Retroperitoneal schwannoma: uncommon location of a benign tumor","volume":"10","author":"Debaibi","year":"2022","journal-title":"Clin. Case Reports"},{"issue":"10","key":"R2-9-20260508","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jscr\/2011.10.1","article-title":"Retroperitoneal schwannoma","volume":"2011","author":"Kapan","year":"2011","journal-title":"J Surg Case Rep"},{"key":"R3-9-20260508","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ijscr.2014.08.015","article-title":"Giant retroperitoneal ancient schwannoma: is preoperative biopsy always mandatory?","volume":"6C","author":"Al Skaini","year":"2015","journal-title":"Int. J. Surg. Case Rep."},{"issue":"9","key":"R4-9-20260508","doi-asserted-by":"crossref","DOI":"10.1177\/0300060520935302","article-title":"A rare case of giant retroperitoneal neurilemmoma","volume":"48","author":"Gao","year":"2020","journal-title":"J. Int. Med. 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Sch."},{"issue":"2","key":"R12-9-20260508","article-title":"Retroperitoneal schwannoma: two rare case reports","volume":"13","author":"Harhar","year":"2021","journal-title":"Cureus"},{"issue":"5","key":"R13-9-20260508","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"Int. J. Surg. Lond. 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