{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T02:21:36Z","timestamp":1792981296324,"version":"4.5.0"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Interstitial ectopic pregnancy is a rare but life-threatening condition, accounting for 2.4 % of all ectopic pregnancies. Diagnosing it can be challenging, as the interstitial portion of the fallopian tube allows for delayed rupture due to its capacity to expand, often leading to significant haemorrhage. Early detection is critical to preventing severe complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We report the case of a 30-year-old primigravida who presented for routine antenatal care at 12 weeks of gestation, asymptomatic with no identifiable risk factors. Routine ultrasound revealed a suspicious gestation near the left uterine horn, leading to a diagnosis of interstitial ectopic pregnancy via MRI. The patient underwent a laparotomy with successful wedge resection and salpingectomy. She recovered well without complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>This case highlights the diagnostic challenges of interstitial ectopic pregnancy, which can remain asymptomatic longer than other types due to the anatomical features of the interstitial segment. Diagnostic imaging is vital for accurate diagnosis, especially in stable patients. Early intervention is key to avoiding catastrophic outcomes like uterine rupture and severe haemorrhage. Advances in imaging and surgical techniques have improved patient outcomes, but careful prenatal follow-up remains crucial for future pregnancies due to the increased risk of uterine rupture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Routine antenatal care and imaging play a pivotal role in the early detection of interstitial ectopic pregnancies. Prompt diagnosis and management can significantly reduce the risk of severe complications, emphasizing the importance of vigilant prenatal monitoring in reducing maternal morbidity and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2024.110688","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T09:26:54Z","timestamp":1732786014000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Interstitial ectopic pregnancy, a rare clinical phenomenon diagnosed asymptomatically on routine work up in Tanzania: Case report"],"prefix":"10.1097","volume":"126","author":[{"given":"Murtaza","family":"Lamuwalla","sequence":"first","affiliation":[{"name":"Family Medicine Resident, The Aga Khan University, East Africa Medical College, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajida","family":"Panjwani","sequence":"additional","affiliation":[{"name":"Family Medicine Resident, The Aga Khan University, East Africa Medical College, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allyzain","family":"Ismail","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Aga Khan Hospital, Dar-es-Salaam, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Samji","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, The Aga Khan Hospital, Dar-es-Salaam, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munawar","family":"Kaguta","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The Aga Khan Hospital, Dar-es-Salaam, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Jaiswal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The Aga Khan Hospital, Dar-es-Salaam, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-49-20260508","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1007\/s00404-013-2929-2","article-title":"Ectopic pregnancy: a review","volume":"288","author":"Rana","year":"2013","journal-title":"Arch. Gynecol. Obstet."},{"issue":"12","key":"R2-49-20260508","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1093\/humrep\/17.12.3224","article-title":"Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases","volume":"17","author":"Bouyer","year":"2002","journal-title":"Hum. Reprod."},{"issue":"8","key":"R3-49-20260508","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/OGX.0b013e31829cdbeb","article-title":"Clinical diagnosis and treatment of ectopic pregnancy","volume":"68","author":"Alkatout","year":"2013","journal-title":"Obstet. Gynecol. Surv."},{"issue":"3","key":"R4-49-20260508","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.rcl.2007.04.009","article-title":"Sonographic evaluation of ectopic pregnancy","volume":"45","author":"Bhatt","year":"2007","journal-title":"Radiol. Clin. North Am."},{"issue":"2","key":"R5-49-20260508","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3390\/medicina59020233","article-title":"Interstitial ectopic pregnancy\u2014case reports and medical management","volume":"59","author":"Kampioni","year":"2023","journal-title":"Medicina"},{"issue":"1","key":"R6-49-20260508","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s10397-018-1054-4","article-title":"The diagnosis and management of interstitial ectopic pregnancies: a review","volume":"16","author":"Brincat","year":"2019","journal-title":"Gynecol. 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Can."},{"issue":"5","key":"R9-49-20260508","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"Int J Surg Lond Engl."},{"issue":"3","key":"R10-49-20260508","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1097\/AOG.0000000000002560","article-title":"Obstetricians ACo, Gynecologists. ACOG Practice Bulletin No. 193: tubal ectopic pregnancy.","volume":"131","year":"2018","journal-title":"Obstet. 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