{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:01:36Z","timestamp":1788220896305,"version":"build-2803163510"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T00:00:00Z","timestamp":1735948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Amyand's hernia is a rare condition defined by the presence of the vermiform appendix within an inguinal hernia sac. The occurrence of Amyand's hernia with testicular necrosis is particularly uncommon, further complicating its clinical presentation and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 50-year-old male presented with a two-year history of progressive right scrotal swelling, acutely worsened over four days with pain and fever. Examination revealed a firm, tender, irreducible right scrotal mass with overlying erythema. Laboratory tests showed leukocytosis. Imaging confirmed an inflamed appendix within the hernial sac, consistent with Amyand's hernia complicated by abscess formation. Emergency surgery revealed a gangrenous appendix, scrotal abscess, and necrotic right testicular tissue. The patient underwent appendectomy, orchiectomy, hernia repair, and abscess drainage. He recovered uneventfully, with symptom resolution and no recurrence at follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>The progression of Amyand's hernia to appendicitis and subsequent perforation, as seen in our case, can result in severe complications, including abscess formation and testicular necrosis. The Losanoff and Basson classification categorizes Amyand's hernia based on the appendix's condition and associated complications, ranging from a normal appendix (Type 1) to severe extra-sac pathology such as gangrene or malignancy (Type 4). Our case aligns with Type 4, involving a perforated appendix with gangrene and a scrotal abscess, necessitating extensive surgical intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights the rarity and complexity of Amyand's hernia in adults, emphasizing the need for prompt recognition and tailored management to achieve favorable outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.110856","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T11:57:36Z","timestamp":1736164656000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Strangulated Amyand's hernia with testicular necrosis in an adult: A case report"],"prefix":"10.1097","volume":"127","author":[{"given":"Ephrem Adane","family":"Andargie","sequence":"first","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suleiman Ayalew","family":"Belay","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Negussie","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiwot Tesfaselassie","family":"Afework","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melaku Tessema","family":"Kassie","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hewan Fiseha","family":"Gebresellassie","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-46-20260325","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.epsc.2016.07.003","article-title":"Amyand's hernia with appendicitis in children: a delayed diagnosis","volume":"13","author":"Jabloun,","year":"2016","journal-title":"J Pediatr Surg Case Rep"},{"issue":"6","key":"R2-46-20260325","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s10029-009-0528-8","article-title":"Amyand's hernia: a series of 30 cases in children","volume":"13","author":"Kaymakci,","year":"2009","journal-title":"Hernia"},{"issue":"6","key":"R3-46-20260325","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.amjsurg.2013.07.043","article-title":"Amyand's hernia: a review","volume":"207","author":"Michalinos,","year":"2014","journal-title":"Am. 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