{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T23:55:36Z","timestamp":1788825336288,"version":"build-2803163510"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>\n                      Amoebic colitis, caused by the protozoan\n                      <jats:italic toggle=\"yes\">Entamoeba histolytica<\/jats:italic>\n                      , is a significant global health concern, ranking as the second leading cause of parasitic infection-related mortality. The disease manifests across a wide clinical spectrum, from asymptomatic carriers to severe necrotizing colitis. Rarely, it can form an inflammatory mass, or ameboma, which may mimic malignancy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We report a case of a 60-year-old female presenting with acute right iliac pain, fever, and nausea, but no diarrhea or recent travel history. Imaging revealed irregular cecal thickening with features suggestive of a perilesional abscess. Exploratory laparotomy identified a 7 cm cecal mass with necrotic tissue, leading to a right hemicolectomy. Histopathology confirmed amoebic colitis with trophozoites in necrotic areas. Postoperative recovery was uneventful with antibiotic therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Ameboma, an uncommon complication of amoebic colitis, poses diagnostic challenges due to its tumor-like appearance. Misdiagnosis is common, especially in non-endemic regions, where clinical and radiological findings often mimic malignancy. Diagnosis requires a combination of serology, stool examination, and biopsy. Treatment is primarily medical, with surgical intervention reserved for complications. Preventive strategies, including sanitation improvements and vaccine development, are crucial to reducing disease burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case underscores the importance of considering amoebiasis in differential diagnoses, even in non-endemic regions. Enhanced diagnostic awareness and preventive measures can significantly improve outcomes and reduce the global health impact of amoebiasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111149","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T04:20:52Z","timestamp":1741839652000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Colic ameboma mimicking colic cancer: A case report"],"prefix":"10.1097","volume":"129","author":[{"given":"Tayssir","family":"KHLIF","sequence":"first","affiliation":[{"name":"Department B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salsabil","family":"NASRI","sequence":"additional","affiliation":[{"name":"Department B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amine Ben","family":"SAFTA","sequence":"additional","affiliation":[{"name":"Department B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farah","family":"HAMZA","sequence":"additional","affiliation":[{"name":"Department of Radiology, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wided","family":"AJOULI","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramzi","family":"NOUIRA","sequence":"additional","affiliation":[{"name":"Department B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-47-20260423","first-page":"539","article-title":"A case of amoebic colitis with amoeboma and simultaneous liver abscesses. A diagnosis by colonoscopy","volume":"82","author":"Bronswijk,","year":"2019","journal-title":"Acta Gastroenterol. Belg."},{"key":"R2-47-20260423","doi-asserted-by":"crossref","first-page":"717","DOI":"10.3855\/jidc.15419","article-title":"Fulminant necrotizing amoebic colitis presenting as acute appendicitis: a case report and comprehensive literature review","volume":"16","author":"Rahadiani,","year":"2022","journal-title":"J. Infect. Dev. Ctries."},{"key":"R3-47-20260423","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000037195","article-title":"A case report of refractory amebic colitis and literature review","volume":"103","author":"Shao,","year":"2024","journal-title":"Medicine (Baltimore)"},{"key":"R4-47-20260423","doi-asserted-by":"crossref","first-page":"228","DOI":"10.4103\/0377-4929.48927","article-title":"Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer","volume":"52","author":"Fernandes,","year":"2009","journal-title":"Indian J. Pathol. Microbiol."},{"issue":"5","key":"R5-47-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"THhe SCARE 2023 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int J Surg Lond Engl."},{"key":"R6-47-20260423","first-page":"14","article-title":"L'Amoebome colique: faut-il y penser plus souvent?","author":"Benmansour,","year":"2013","journal-title":"Pan Afr. Med. J."},{"key":"R7-47-20260423","doi-asserted-by":"crossref","DOI":"10.1093\/jscr\/rjy124","article-title":"Cecal ameboma mimicking obstructing colonic carcinoma","volume":"2018","author":"Almalki","year":"2018","journal-title":"J Surg Case Rep"},{"key":"R8-47-20260423","doi-asserted-by":"crossref","first-page":"A28","DOI":"10.1016\/j.cgh.2009.02.026","article-title":"Cecal Ameboma","volume":"8","author":"Joshi,","year":"2010","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"R9-47-20260423","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1056\/NEJMra022710","article-title":"Amebiasis","volume":"348","author":"Haque,","year":"2003","journal-title":"N. Engl. J. Med."}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2025.111149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:54:18Z","timestamp":1786035258000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2025.111149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":9,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2025.111149","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2025-02-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}