{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T21:39:54Z","timestamp":1776980394937,"version":"3.51.4"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Synovial chondromatosis is a rare, benign metaplasia of the synovium characterized by the formation of cartilaginous nodules. This condition can lead to joint stiffness, pain, and damage. It is most common in the knee but has been described in various joints, including the hand. Due to its low prevalence and nonspecific symptoms, delayed diagnosis may lead to complications such as local invasion, pain, osteoarthritis, and, rarely, malignant transformation. Surgical intervention is often indicated after conservative management fails.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report:<\/jats:title>\n                    <jats:p>This report describes the complex case of synovial chondromatosis of the second metacarpophalangeal (MCP) joint in an 18-year-old female. Multiple surgical interventions culminated in amputation of her second ray for definitive management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>This case underscores the complexities of diagnosing and managing synovial chondromatosis, particularly in rare locations like the hand. Despite radiographic and pathological evidence, a definitive diagnosis was delayed, contributing to prolonged morbidity. The aggressive and recurring nature of this case highlights the need to consider synovial chondromatosis in refractory hand and finger joint pain, regardless of patient age or gender. Questions remain about whether earlier aggressive intervention could reduce recurrence or if earlier amputation could improve outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case highlights the challenges of diagnosing and managing recurrent synovial chondromatosis in the hand. Early recognition and aggressive intervention may prevent prolonged morbidity and functional impairment. Further research is needed to determine whether earlier amputation could improve outcomes in refractory cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111164","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T13:39:40Z","timestamp":1742218780000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent synovial chondromatosis in the hand leading to second ray amputation: A case report"],"prefix":"10.1097","volume":"129","author":[{"given":"Mallory","family":"Rongstad","sequence":"first","affiliation":[{"name":"Drexel University College of Medicine, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jarod","family":"Moyer","sequence":"additional","affiliation":[{"name":"University of Wisconsin Hospitals and Clinics, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Mifflin","sequence":"additional","affiliation":[{"name":"University of Wisconsin Hospitals and Clinics, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Condit","sequence":"additional","affiliation":[{"name":"University of Wisconsin Hospitals and Clinics, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt","family":"Rongstad","sequence":"additional","affiliation":[{"name":"University of Wisconsin Hospitals and Clinics, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"6","key":"R2-62-20260423","first-page":"NP1","article-title":"Primary distal interphalangeal joint tenosynovial chondromatosis of the small finger: a case report with literature review","volume":"17","author":"Benvenuti,","year":"2022","journal-title":"Hand (N. 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Case Stud."},{"issue":"5","key":"R6-62-20260423","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1148\/rg.275075116","article-title":"Imaging of synovial chondromatosis with radiologic-pathologic correlation","volume":"27","author":"Murphey,","year":"2007","journal-title":"Radiographics"},{"key":"R7-62-20260423","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/647939","article-title":"Synovial chondrosarcoma arising in synovial chondromatosis","volume":"2014","author":"Evans,","year":"2014","journal-title":"Sarcoma"},{"issue":"3-4","key":"R9-62-20260423","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s004020050056","article-title":"Tenosynovial chondromatosis of the third finger","volume":"120","author":"Gil-Albarova,","year":"2000","journal-title":"Arch. Orthop. Trauma Surg."},{"issue":"5","key":"R10-62-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg. Lond. Engl."},{"key":"R11-62-20260423","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.ijsu.2018.10.031","article-title":"The PROCESS 2018 statement: updating consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) guidelines","volume":"60","author":"Agha,","year":"2018","journal-title":"Int. J. 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