{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T21:40:09Z","timestamp":1776980409037,"version":"3.51.4"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Polyarteritis Nodosa (PAN) is a rare vasculitis of medium-sized arteries with severe complications, including Renal artery aneurysm (RAA)rupture and gastrointestinal ischemia. Early recognition and intervention are crucial for improving outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>A 21-year-old male with a history of PAN presented with acute flank pain, rash, confusion, and anemia. Imaging revealed a ruptured RAA with retroperitoneal hemorrhage. He developed bowel ischemia confirmed by colonoscopy and computed tomography scan. The patient underwent renal artery embolization and exploratory laparotomy, revealing gangrenous cecum and ileal perforation, requiring hemicolectomy and ileal resection. Postoperatively, he was treated with immunoglobulin, cyclophosphamide, and prednisone, resulting in significant improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>PAN can cause life-threatening complications, including vascular rupture and ischemia. Embolization effectively controlled bleeding, and surgery addressed ischemic damage. Early intervention with immunosuppressive therapy played a key role in recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case emphasizes the need for prompt recognition and treatment of severe PAN complications. Early surgical intervention and appropriate immunosuppressive therapy are essential for preventing fatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111172","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T13:36:56Z","timestamp":1742305016000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Complex presentation of polyarteritis nodosa: Renal pseudoaneurysm rupture and bowel ischemia: A case report"],"prefix":"10.1097","volume":"129","author":[{"given":"Ali F.","family":"Rabaya","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Hebron University, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kareem","family":"Ibraheem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Shawer","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mutasem N.","family":"Nairat","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hebron University, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayf","family":"Sayes","sequence":"additional","affiliation":[{"name":"General Surgery Department, Ahli Hospital, Hebron, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafiq","family":"Salhab","sequence":"additional","affiliation":[{"name":"General Surgery Department, Ahli Hospital, Hebron, Palestine; Faculty of Medicine, Palestine Polytechnic University, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"34","key":"R1-69-20260423","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000039445","article-title":"Polyarteritis nodosa complicated by renal aneurysm and intestinal perforation: a case report","volume":"103","author":"Ma,","year":"2024","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"R2-69-20260423","doi-asserted-by":"crossref","DOI":"10.1016\/j.berh.2023.101845","article-title":"Classification and epidemiology of vasculitis: emerging concepts","volume":"37","author":"Ecclestone,","year":"2023","journal-title":"Best Pract. 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