{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T11:54:59Z","timestamp":1783770899924,"version":"3.55.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Epidermoid cysts are benign, keratin-filled lesions that rarely occur in the genital region. Diagnosis is primarily clinical, but histopathological examination is essential for confirmation. This case highlights a rare occurrence of an epidermoid cyst on the penis, emphasizing clinical features, diagnostic approach, and treatment outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 35-year-old male presented with a non-tender, firm, well-circumscribed lesion measuring 2.5 cm \u00d7 1.8 cm located on the middle third of the left lateral aspect of the penis. Over eight months, the mass grew, causing pruritus, sexual discomfort, and self-image concerns, without pain or infection. Histopathological analysis confirmed the diagnosis of an epidermoid cyst, with stratified squamous epithelium and keratin-filled cystic spaces.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Although rare in the genital area, epidermoid cysts must be considered in the differential diagnosis of penile lesions. Clinical presentation, including a well-defined, mobile mass, is suggestive of the condition. Histopathological features, such as a cyst lined with squamous epithelium and keratin, are key to distinguishing it from other conditions like squamous cell carcinoma. Surgical excision with a margin is the treatment of choice, and recurrence is uncommon when performed adequately.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Epidermoid cysts of the penis are benign lesions with a favorable prognosis following surgical excision. This case demonstrates the importance of accurate diagnosis and management to avoid misdiagnosis and ensure successful treatment outcomes. The patient showed no recurrence at the 6-month follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111181","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T20:58:02Z","timestamp":1742331482000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Epidermoid cyst of the penis: A case report"],"prefix":"10.1097","volume":"129","author":[{"given":"Salim","family":"Lachkar","sequence":"first","affiliation":[{"name":"Department of Urology A, Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imad","family":"Boualaoui","sequence":"additional","affiliation":[{"name":"Department of Urology A, Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Ibrahimi","sequence":"additional","affiliation":[{"name":"Department of Urology A, Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syrine","family":"Hamada","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hachem","family":"El Sayegh","sequence":"additional","affiliation":[{"name":"Department of Urology A, Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yassine","family":"Nouini","sequence":"additional","affiliation":[{"name":"Department of Urology A, Ibn Sina University Hospital, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"5","key":"R1-77-20260423","first-page":"PD05","article-title":"Penile epidermal cyst: a case report","volume":"10","author":"Kumaraguru,","year":"2016","journal-title":"J. Clin. Diagn. Res."},{"key":"R2-77-20260423","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijscr.2024.109521","article-title":"A case report of an epidermoid inclusion cyst following repair of hypospadias","volume":"118","author":"Gondal,","year":"2024","journal-title":"Int. J. Surg. Case Rep."},{"issue":"8","key":"R3-77-20260423","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/cup.14644","article-title":"Proliferating inverted follicular keratosis of genital skin: case series of a challenging variant","volume":"51","author":"Huang,","year":"2024","journal-title":"J. Cutan. Pathol."},{"issue":"6","key":"R4-77-20260423","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1177\/1066896920916242","article-title":"A subcentimetric nodule on the penile shaft","volume":"28","author":"Majumder,","year":"2020","journal-title":"Int. J. Surg. Pathol."},{"issue":"7","key":"R5-77-20260423","article-title":"Acquired penile epidermoid cysts in children","volume":"14","author":"Yagmur,","year":"2022","journal-title":"Cureus"},{"key":"R6-77-20260423","article-title":"Penile epidermal inclusion cyst mimicking ectopic testis mass: a case report","volume":"40","author":"Firdaus,","year":"2022","journal-title":"Urol Case Rep"},{"issue":"1","key":"R7-77-20260423","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/s13256-019-2133-5","article-title":"Median raphe cyst of the penis: a case report and review of the literature","volume":"13","author":"Syed,","year":"2019","journal-title":"J. Med. Case Rep."},{"issue":"1","key":"R8-77-20260423","doi-asserted-by":"crossref","first-page":"80","DOI":"10.4103\/ajps.ajps_142_21","article-title":"Preputial cyst in the newborn: a case report from Africa","volume":"20","author":"Elebute,","year":"2023","journal-title":"Afr. J. Paediatr. Surg."},{"issue":"3","key":"R9-77-20260423","doi-asserted-by":"crossref","first-page":"314","DOI":"10.4103\/UA.UA_92_18","article-title":"Median raphe cyst of the penis: a startling diagnosis for the unaccustomed clinician","volume":"11","author":"Alphones,","year":"2019","journal-title":"Urol Ann"},{"issue":"1","key":"R10-77-20260423","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1186\/s13256-018-1930-6","article-title":"An epidermal cyst of the penis after distal hypospadias surgery: a case report","volume":"12","author":"Guler,","year":"2018","journal-title":"J. Med. Case Rep."},{"key":"R11-77-20260423","first-page":"56","article-title":"Epidermoid cyst on frenulum of the penis: a case report","volume":"21","author":"Tirtayasa,","year":"2018","journal-title":"Urol Case Rep"},{"issue":"9","key":"R12-77-20260423","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1111\/j.1743-6109.2008.00888.x","article-title":"Penile epidermal inclusion cyst: a late complication of penile girth enhancement surgery","volume":"5","author":"Park,","year":"2008","journal-title":"J. Sex. Med."},{"issue":"1","key":"R13-77-20260423","article-title":"Analysis of related factors between the occurrence of secondary epidermoid cyst of penis and circumcision","volume":"12","author":"Yu,","year":"2022","journal-title":"Sci. Rep."},{"issue":"3","key":"R14-77-20260423","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1053\/j.semdp.2014.12.014","article-title":"Clinicopathological features and histogenesis of penile cysts","volume":"32","author":"Lezcano,","year":"2015","journal-title":"Semin. Diagn. Pathol."},{"key":"R15-77-20260423","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2024.149065","article-title":"Gardner syndrome in a Tunisian family: identification of a rare APC mutation through targeted NGS","volume":"935","author":"Abdelmaksoud-Dammak,","year":"2025","journal-title":"Gene"},{"issue":"1","key":"R16-77-20260423","doi-asserted-by":"crossref","first-page":"122","DOI":"10.4103\/ijd.ijd_968_21","article-title":"Inverted follicular keratosis: a retrospective study over 10 years","volume":"68","author":"Baklouti,","year":"2023","journal-title":"Indian J. Dermatol."},{"issue":"2","key":"R17-77-20260423","first-page":"152","article-title":"Human papillomavirus: screening, testing, and prevention","volume":"104","author":"Quinlan,","year":"2021","journal-title":"Am. Fam. Physician"},{"issue":"6","key":"R18-77-20260423","doi-asserted-by":"crossref","first-page":"692","DOI":"10.4103\/ijd.ijd_101_21","article-title":"Superficial penile leiomyosarcoma mimicking a benign tumor","volume":"66","author":"Haruki,","year":"2021","journal-title":"Indian J. Dermatol."},{"key":"R19-77-20260423","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1186\/1752-1947-8-179","article-title":"Epidermoid cyst of the coronal sulcus mimicking penile cancer: a case report","volume":"8","author":"Cormio,","year":"2014","journal-title":"J. Med. Case Rep."},{"issue":"5","key":"R20-77-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg."}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003670?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003670?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2025.111181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T21:01:23Z","timestamp":1776978083000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2025.111181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":20,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2025.111181","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2025-02-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}