{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:43:06Z","timestamp":1787787786570,"version":"build-2784847793"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T00:00:00Z","timestamp":1742256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Primary hyperparathyroidism is a common endocrine disorder, especially among postmenopausal women, characterized by elevated calcium levels and excessive secretion of parathyroid hormone due to hyperactive parathyroid glands.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>A 17-year-old male presented with a painless mass in the maxilla, which developed six months after a cystic lesion was diagnosed in his right knee. Subsequent examinations identified a parathyroid tumor, leading to surgical excision of the right lower parathyroid gland, and the patient developed hypocalcemia postoperatively, indicative of Hungry Bone Syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Primary hyperparathyroidism occurs mostly in females aged 50 to 60 and presents with many clinical symptoms and signs, but our patient was a 17-year-old male and had one of the complications of this disease, which is a brown tumor, without the appearance of the common typical symptoms of the disease, which led to excluding the diagnosis of a brown tumor and suspecting a giant cell tumor due to the histological similarity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case report emphasizes the critical need to consider primary hyperparathyroidism in atypical demographics, such as young males. Notably, the formation of a brown tumor prior to overt hyperparathyroidism symptoms suggests potential early complications. This case reinforces the importance of surgical expertise in successful parathyroidectomy in countries without advanced imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphical abstract<\/jats:title>\n                    <jats:p>JOURNAL\/ijscr\/04.03\/01612930-202504000-00078\/figure1\/v\/2026-04-23T194637Z\/r\/image-jpeg<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111182","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T20:20:56Z","timestamp":1742588456000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Bone tumors in the maxilla and the tibia leading to the diagnosis of asymptomatic primary hyperparathyroidism in a 17-year-old male: A case report"],"prefix":"10.1097","volume":"129","author":[{"given":"Saja","family":"Karaja","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Hama University, Hama, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Borghol","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hama University, Hama, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahed","family":"Assaf","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hama University, Hama, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabeha Haytham","family":"Alibrahim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hama National Hospital, Hama, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maram","family":"Alkirwan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Hama National Hospital, Hama, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Shannat","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Faculty of Medicine, Hama University, Hama, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"5","key":"R1-78-20260423","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.main.2015.06.005","article-title":"Primary hyperparathyroidism associated with a giant cell tumor: one case in the distal radius","volume":"34","author":"Ouzaa,","year":"2015","journal-title":"Chir. Main"},{"issue":"1","key":"R2-78-20260423","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.1038\/s41598-025-86954-4","article-title":"Calcium to magnesium ratio as a superior biomarker for nephrolithiasis detection in primary hyperparathyroidism","volume":"15","author":"Yal\u00e7\u0131n,","year":"2025","journal-title":"Sci. Rep."},{"issue":"4","key":"R6-78-20260423","doi-asserted-by":"crossref","first-page":"614","DOI":"10.3803\/EnM.2015.30.4.614","article-title":"Primary hyperparathyroidism with extensive brown tumors and multiple fractures in a 20-year-old woman","volume":"30","author":"Choi,","year":"2015","journal-title":"Endocrinol Metab (Seoul)"},{"issue":"5","key":"R8-78-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int J Surg Lond Engl."}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003682?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003682?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2025.111182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T21:01:26Z","timestamp":1776978086000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2025.111182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":4,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2025.111182","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2025-02-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}