{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:08:30Z","timestamp":1786118910107,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Lipodystrophies are conditions characterized by a loss of subcutaneous fat, which can be congenital or acquired, and present in various patterns of fat distribution. Accurate diagnosis is essential for identifying comorbidities and ensuring appropriate multidisciplinary care and targeted treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 34-year-old female experienced significant facial changes and increased abdominal fat over five years. She had lumps under her armpits discharging white fluid, with clinical findings of low hemoglobin and accessory breast tissue, which was surgically excised.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Acquired generalized lipodystrophy is often overlooked, with over 250 documented cases. It typically presents in adolescence and involves symmetrical fat loss, with potential associations to autoimmune diseases and unique features in this case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case emphasizes the complexities of acquired lipodystrophy, especially regarding accessory breast tissue. It highlights the need for thorough evaluations and increased awareness among healthcare providers for timely diagnosis and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111202","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T14:20:56Z","timestamp":1742998856000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Acquired partial lipodystrophy (Barraquer-Simons syndrome) with both-side axillary breasts: A case report"],"prefix":"10.1097","volume":"129","author":[{"given":"Mohammad","family":"Al-Jawad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Mawaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada","family":"Mawaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam","family":"Krimsty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silva","family":"Ishkanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"3","key":"R2-95-20260423","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ando.2024.05.015","article-title":"Partial lipodystrophy: clinical presentation and treatment","volume":"85","author":"Mosbah,","year":"2024","journal-title":"Ann. Endocrinol. (Paris)"},{"issue":"5","key":"R4-95-20260423","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi,","year":"2023","journal-title":"Int. J. Surg. [Internet]."},{"issue":"11","key":"R5-95-20260423","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.1210\/jc.2011-1159","article-title":"Clinical review#: lipodystrophies: genetic and acquired body fat disorders","volume":"96","author":"Garg,","year":"2011","journal-title":"J. Clin. Endocrinol. Metab. [Internet]."},{"issue":"7","key":"R6-95-20260423","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1002\/ajmg.a.36491","article-title":"Barraquer-Simons syndrome: a rare clinical entity","volume":"164","author":"Simsek-Kiper,","year":"2014","journal-title":"Am. J. Med. Genet. A [Internet]."},{"issue":"12","key":"R8-95-20260423","doi-asserted-by":"crossref","first-page":"4500","DOI":"10.1210\/jc.2016-2466","article-title":"The diagnosis and management of lipodystrophy syndromes: a multi-society practice guideline","volume":"101","author":"Brown,","year":"2016","journal-title":"J. Clin. Endocrinol. Metab. [Internet]."},{"issue":"1","key":"R9-95-20260423","article-title":"To absorb fat - supersize my lipid droplets","volume":"129","author":"Goldberg,","year":"2019","journal-title":"J. Clin. Invest. [Internet]"},{"issue":"2","key":"R10-95-20260423","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1530\/JOE-18-0361","article-title":"The depot-specific and essential roles of CBP\/p300 in regulating adipose plasticity","volume":"240","author":"Namwanje,","year":"2019","journal-title":"J. Endocrinol. [Internet]"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225003888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2025.111202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:54:09Z","timestamp":1786035249000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijscr.2025.111202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":7,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2025.111202","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2025-03-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}