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This case presents a unique instance of spontaneous uterine rupture in a multiparous woman without typical risk factors, highlighting the challenges of diagnosis and management in a resource-limited setting. The associated fetal cyclopia adds to the rarity of the case and contributes to the existing literature on uterine rupture. This report demonstrates the need for high clinical suspicion and prompt intervention, even in the absence of usual risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>A 30-year-old, gravida 7, para 6 female presented with a two-day history of abdominal pain, vomiting, and subjective fever. The patient progressed to hemodynamic instability, vaginal bleeding, and loss of consciousness within a few hours of admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>The main diagnosis was spontaneous uterine rupture with hemoperitoneum and a non-viable fetus with cyclopia. The therapeutic interventions included emergency exploratory laparotomy, evacuation of the hemoperitoneum, and subtotal hysterectomy. The patient recovered well and was discharged on postoperative day five.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This case underscores the unpredictable nature of uterine rupture and the importance of maintaining a high index of suspicion for this diagnosis, even in the absence of typical risk factors, particularly in resource-limited settings. Prompt surgical intervention and appropriate postoperative care are essential for favorable maternal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111228","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T04:21:18Z","timestamp":1743049278000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Spontaneous uterine rupture in the second trimester with fetal Cyclopia at a resource-limited setting: A case report"],"prefix":"10.1097","volume":"130","author":[{"given":"Mohamed Ahmed","family":"Abdillahi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Abdi Aw","family":"Egge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaltu Resassa","family":"Shashe","sequence":"additional","affiliation":[{"name":"Al-Hayat Teaching and Research Hospital, Amoud University, Amoud Valley, Borama 25263, Somaliland, Somalia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenzu Bedru","family":"Hussen","sequence":"additional","affiliation":[{"name":"Al-Hayat Teaching and Research Hospital, Amoud University, Amoud Valley, Borama 25263, Somaliland, Somalia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdisalam Aden","family":"Dahir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdisalam Hassan","family":"Muse","sequence":"additional","affiliation":[{"name":"Research and Innovation Centre, Amoud University, Amoud Valley, Borama 25263, Somaliland, Somalia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-11-20260304","article-title":"A rare and unique case report of lateral Uterine Wall rupture and its review","volume":"15","author":"Agarwal","year":"2023","journal-title":"Cureus"},{"key":"R2-11-20260304","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-018-1761-x","article-title":"Spontaneous uterine rupture and surgical repair at 21 weeks gestation with progression to live birth: a case report","volume":"18","author":"Hawkins","year":"2018","journal-title":"BMC Pregnancy Childbirth"},{"key":"R3-11-20260304","doi-asserted-by":"crossref","first-page":"3532","DOI":"10.3390\/jcm12103532","article-title":"Unexpected uterine rupture\u2014a case report, review of the literature and clinical suggestions","volume":"12","author":"Flis","year":"2023","journal-title":"J. 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