{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T08:32:01Z","timestamp":1773304321735,"version":"3.50.1"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T00:00:00Z","timestamp":1747612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>\n                      Lemierre syndrome is characterized by clinical or radiographic signs of thrombosis of the internal jugular vein, distant infected emboli and the presence of anaerobic pathogens, usually\n                      <jats:italic toggle=\"yes\">Fusobacterium necrophorum<\/jats:italic>\n                      . It can be the result of a recent infection in the area of the head or neck, mostly in the form of pharyngitis or tonsillitis. It can also result from less common conditions, such as odontogenic infections which is rarely reported in the dental literature.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>This article reports the clinical case of a 69-year-old male patient with a persistent diffuse swelling in the facial and neck area with throat pain, associated to an odontogenic sinusitis, that was later diagnosed as Lemierre's syndrome caused by an impacted maxillary wisdom tooth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Diagnosis of Lemierre syndrome is challenging. Suspicion of the disease is needed in cases of oropharyngeal infection followed by fever, tender swelling of the neck sore throat and dysphagia. Screening for thrombosis of the internal jugular vein may be quickly accomplished using ultrasonography; however, a computed tomography scan is more sensitive for identifying this entity.<\/jats:p>\n                    <jats:p>Successful management of this condition relies on knowledge of the condition and its prompt diagnosis. This usually needs surgical drainage and intravenous antibiotics. Anticoagulation is controversial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Morbidity and mortality are significant with this syndrome, that is why diagnosis and early treatment are very important, and dentists should be familiar with this condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111457","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T11:54:27Z","timestamp":1747742067000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A rare case report of Lemierre syndrome originating from an impacted maxillary third molar"],"prefix":"10.1097","volume":"132","author":[{"given":"Benjelloun","family":"Laila","sequence":"first","affiliation":[{"name":"Oral Surgery Department, Mohamed V University of Rabat, Faculty of Dentistry, Avenue Mohamed El Jazouli, 6212 Madinat Al Irfane, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"El Farouki","family":"Ayman","sequence":"additional","affiliation":[{"name":"Radiology Department, Mohamed V Military Hospital, Av. Abderrahim Bouabid, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taleb","family":"Bouchra","sequence":"additional","affiliation":[{"name":"Oral Surgery Department, Mohamed V University of Rabat, Faculty of Dentistry, Avenue Mohamed El Jazouli, 6212 Madinat Al Irfane, Rabat, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-22-20260311","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jmii.2019.10.002","article-title":"Lemierre syndrome complicating deep neck infection and descending necrotizing mediastinits caused by odontogenic infections","volume":"53","author":"Li","year":"2020","journal-title":"J. Microbiol. Immunol. Infect"},{"key":"R2-22-20260311","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4103\/2231-0746.175746","article-title":"Lemierre's syndrome from odontogenic infection: review of the literature and case description","volume":"5","author":"Noy","year":"2015","journal-title":"Ann. Maxillofac. Surg"},{"key":"R3-22-20260311","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.2169\/internalmedicine.54.4126","article-title":"Lemierre's syndrome associated with periodontal injury-derived odontogenic infection that did not respond to meropenem","volume":"54","author":"Oya","year":"2015","journal-title":"Intern. Med"},{"key":"R4-22-20260311","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/scd.12399","article-title":"Thoracic pain associated with an odontogenic infection: an unusual Lemierre's syndrome","volume":"39","author":"Scopel Costa","year":"2019","journal-title":"Spec. Care Dentist"},{"key":"R5-22-20260311","first-page":"394","article-title":"Lemierre syndrome associated with dental infections. Report of one case and review of the literature","volume":"12","author":"Ju\u00e1rez Escalona","year":"2007","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"R6-22-20260311","first-page":"1","article-title":"Lemierre Syndrome From an Odontogenic Source: A Review for Dentists","volume":"76","author":"Albilia","year":"2010"},{"key":"R7-22-20260311","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.3390\/biology11121784","article-title":"Complications of severe odontogenic infections: a review","volume":"11","author":"Neal","year":"2022","journal-title":"Biology"},{"key":"R8-22-20260311","doi-asserted-by":"crossref","first-page":"136","DOI":"10.4103\/0975-5950.183867","article-title":"A review of complications of odontogenic infections","volume":"6","author":"Bali","year":"2015","journal-title":"Natl. J. Maxillofac. Surg"},{"key":"R9-22-20260311","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1097\/JS9.0000000000000373","article-title":"The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"109","author":"Sohrabi","year":"2023","journal-title":"Int. J. Surg. Lond. Engl"},{"key":"R10-22-20260311","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1086\/313970","article-title":"Human necrobacillosis, with emphasis on Lemierre's syndrome","volume":"31","author":"Hagelskjaer Kristensen","year":"2000","journal-title":"Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am"},{"key":"R11-22-20260311","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1002\/lary.20542","article-title":"Lemierre's syndrome: a systematic review","volume":"119","author":"Karkos","year":"2009","journal-title":"Laryngoscope"},{"key":"R12-22-20260311","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1097\/MLG.0b013e318093ee0e","article-title":"Lemierre syndrome: two cases and a review","volume":"117","author":"Syed","year":"2007","journal-title":"Laryngoscope"},{"key":"R13-22-20260311","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.joms.2006.03.015","article-title":"Severe odontogenic infections, part 1: prospective report","volume":"64","author":"Flynn","year":"2006","journal-title":"J. Oral Maxillofac. Surg. Off. J. Am. Assoc. Oral Maxillofac. Surg"},{"key":"R14-22-20260311","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.thromres.2020.10.002","article-title":"Lemierre syndrome: current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry","volume":"196","author":"Valerio","year":"2020","journal-title":"Thromb. Res"},{"key":"R15-22-20260311","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/adj.12062","article-title":"Lemierre's syndrome: a serious complication of a routine dental procedure","volume":"58","author":"Ghaly","year":"2013","journal-title":"Aust. Dent. J"},{"key":"R16-22-20260311","article-title":"Jugular vein thrombosis and anticoagulation therapy in Lemierre's syndrome\u2014a post hoc observational and population-based study of 82 patients","volume":"8","author":"Nygren","year":"2020","journal-title":"Open Forum Infect. 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