{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:59:28Z","timestamp":1773215968383,"version":"3.50.1"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T00:00:00Z","timestamp":1749254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Adenoid cystic carcinomas (ACC) arising from minor salivary glands is rare, comprising only 10\u201320 % of all ACC cases. Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare tumor, accounting for &lt;5 % of head and neck adenoid cystic carcinomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>We report the case of a 68-year-old man, complained from headache with bilateral nasal obstruction and deterioration of the general state, nasal endoscopy and sinonasal imaging revealed a locally advanced NACC infiltrating the skull base.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Treatment for these tumors generally based on radiation, as radical surgical resection is generally difficult and carries significant morbidity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>NACC is a rare disease that causes significant morbidity when it invades the base of the skull. Complete surgical resection is the main treatment for ACC, and may be combined with radiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111497","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T11:15:49Z","timestamp":1750331749000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Nasopharyngeal adenoid cystic carcinoma with skull base involvement: A case-report and review of the literature"],"prefix":"10.1097","volume":"133","author":[{"given":"Achraf Amine","family":"Sbai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima Zahra","family":"Es-sahli","sequence":"additional","affiliation":[{"name":"Department of Ear Nose and Throat, Mohammed VI University Hospital, Medical School, Mohammed the First University, Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Drissia","family":"Belfadil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adil Abdenbi","family":"Tsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeddine","family":"Lachkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahd","family":"Elayoubi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-4-20260310","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1017\/S0022215116008124","article-title":"Clinical outcomes of adenoid cystic carcinoma of the head and neck: a single institution 20-year experience","volume":"130","author":"Ali","year":"2016","journal-title":"J. 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Otol"},{"key":"R2-4-20260310","article-title":"Revised Surgical CAse REport (SCARE) guideline: an update for the age of Artificial Intelligence","volume":"10","author":"Kerwan","year":"2025","journal-title":"Premier Journal of Science"},{"key":"R3-4-20260310","doi-asserted-by":"crossref","first-page":"4444","DOI":"10.1002\/cncr.27408","article-title":"Adenoid cystic carcinoma of the head and neck: incidence and survival trends based on 1973-2007 Surveillance, Epidemiology, and End Results data","volume":"118","author":"Ellington","year":"2012","journal-title":"Cancer"},{"issue":"7","key":"R4-4-20260310","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1080\/0284186X.2018.1426878","article-title":"Treatment approaches for nasopharyngeal adenoid cystic carcinoma","volume":"57","author":"Jeffrey","year":"2018","journal-title":"Acta Oncol"},{"key":"R5-4-20260310","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.amsu.2018.04.004","article-title":"Nasopharyngeal adenoid cystic carcinoma, suggestion of therapeutic innovations: a case report and review of literature","author":"Tatari","year":"2018","journal-title":"Ann. 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