{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:57:11Z","timestamp":1773215831133,"version":"3.50.1"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Anesthetic management of pheochromocytoma is challenging due to the risk of severe hemodynamic instability. Recent evidence suggests an association with Takotsubo syndrome, complicating perioperative care. Awareness of this complication is crucial for optimizing management and improving outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We report a 42-year-old female undergoing preoperative evaluation for an adrenal mass, diagnosed as pheochromocytoma. Echocardiography revealed dilated cardiomyopathy consistent with Takotsubo syndrome. Preoperative optimization included alpha- and beta-blockade. Anesthetic management focused on maintaining hemodynamic stability with invasive monitoring. The surgery was uneventful, and the patient recovered in the intensive care unit with gradual improvement in cardiac function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>This case illustrates the link between pheochromocytoma and Takotsubo syndrome, likely triggered by catecholamine excess. It highlights the importance of careful preoperative preparation and vigilant intraoperative monitoring to minimize cardiovascular complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Takotsubo syndrome should be considered in patients with pheochromocytoma due to its impact on anesthetic management. Comprehensive perioperative care is essential for successful outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111544","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T11:15:49Z","timestamp":1750331749000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Anesthetic management of pheochromocytoma complicated by Takotsubo syndrome: A case report about a dual challenge"],"prefix":"10.1097","volume":"133","author":[{"given":"A.","family":"Bouaiyda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Jeddab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Mounir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Jaafari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bensghir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Balkhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-43-20260310","first-page":"43","article-title":"Manifestations cardiaques des ph\u00e9ochromocytomes. Annales d'Endocrinologie","volume":"70","author":"Luca","year":"2009"},{"key":"R2-43-20260310","article-title":"Revised surgical CAse REport (SCARE) guideline: an update for the age of artificial intelligence","volume":"10","author":"Kerwan","year":"2025","journal-title":"Premier Journal of Science"},{"key":"R3-43-20260310","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0140-6736(05)67139-5","volume":"366","author":"Lenders","year":"2005","journal-title":"Phaeochromocytoma. Lancet"},{"key":"R4-43-20260310","doi-asserted-by":"crossref","first-page":"151","DOI":"10.11604\/pamj.2015.22.151.7505","article-title":"Syndrome coronaire aigu: un mode de r\u00e9v\u00e9lation peu fr\u00e9quent du ph\u00e9ochromocytome","volume":"22","author":"Bouazzaoui","year":"2015","journal-title":"Pan Afr. Med. J"},{"key":"R5-43-20260310","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1093\/ejcts\/ezw122","article-title":"Cardiogenic shock induced by a voluminous phaeochromocytoma rescued by concomitant extracorporeal life support and open left adrenalectomy","volume":"50","author":"Dang Van","year":"2016","journal-title":"Eur. J. Cardiothorac. Surg"},{"key":"R6-43-20260310","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ijcard.2006.07.125","article-title":"A case of transient left ventricular ballooning with pheochromocytoma, supporting pathogenetic role of catecholamines in stress-induced cardiomyopathy or takotsubo cardiomyopathy","volume":"114","author":"Takizawa","year":"2007","journal-title":"Int. J. Cardiol"},{"key":"R7-43-20260310","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1540-8183.2010.00551.x","article-title":"Pheochromocytoma presenting with Takotsubo syndrome: PHEOCHROMOCYTOMA WITH TAKOTSUBO SYNDROME","volume":"23","author":"Marcovitz","year":"2010","journal-title":"J. Interv. Cardiol"},{"key":"R8-43-20260310","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1093\/eurheartj\/ehy076","article-title":"International expert consensus document on Takotsubo syndrome (part I): clinical characteristics, diagnostic criteria, and pathophysiology","volume":"39","author":"Ghadri","year":"2018","journal-title":"Eur. Heart J"},{"key":"R9-43-20260310","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.105.581108","article-title":"Pheochromocytoma-related cardiomyopathy: inverted Takotsubo contractile pattern","author":"Sanchez-Recalde","year":"2006","journal-title":"Circulation"},{"key":"R10-43-20260310","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1054\/jcaf.2002.129267","article-title":"Adrenergic pathways and left ventricular remodeling","volume":"8","author":"Dorn","year":"2002","journal-title":"J. Card. Fail"},{"key":"R11-43-20260310","first-page":"244","article-title":"Pheochromocytoma underlying hypertension, stroke, and dilated cardiomyopathy","volume":"34","author":"Lin","year":"2007","journal-title":"Tex. Heart Inst. J"},{"key":"R12-43-20260310","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1139\/y82-207","article-title":"Role of free radicals in catecholamine-induced cardiomyopathy","volume":"60","author":"Singal","year":"1982","journal-title":"Can. J. Physiol. Pharmacol"},{"key":"R13-43-20260310","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ancard.2004.05.001","article-title":"Syndromes coronariens aigus et ph\u00e9ochromocytome","volume":"53","author":"Tournoux","year":"2004","journal-title":"Ann. Cardiol. Angeiol"},{"key":"R14-43-20260310","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.revmed.2007.06.009","article-title":"Toxicit\u00e9 myocardique des cat\u00e9cholamines: \u00e0 propos de deux observations","volume":"28","author":"Schiano","year":"2007","journal-title":"Rev. Med. Interne"},{"key":"R15-43-20260310","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.annfar.2006.10.006","article-title":"Syndrome de tako-tsubo: \u00e0 propos d'une observation","volume":"26","author":"Mardelle","year":"2007","journal-title":"Ann. Fr. Anesth. Reanim"},{"key":"R16-43-20260310","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1210\/jc.2012-3020","article-title":"Pheochromocytoma crisis is not a surgical emergency","volume":"98","author":"Scholten","year":"2013","journal-title":"J. Clin. Endocrinol. Metab"},{"key":"R17-43-20260310","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1053\/j.jvca.2017.02.023","article-title":"Perioperative Management of Pheochromocytoma","volume":"31","author":"Naranjo","year":"2017","journal-title":"J. Cardiothorac. Vasc. Anesth"},{"key":"R18-43-20260310","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.urology.2016.10.012","article-title":"Preoperative levels of Catecholamines and Metanephrines and intraoperative hemodynamics of patients undergoing Pheochromocytoma and Paraganglioma resection","volume":"100","author":"Weingarten","year":"2017","journal-title":"Urology"},{"key":"R19-43-20260310","doi-asserted-by":"crossref","first-page":"317","DOI":"10.4103\/0970-9185.161665","article-title":"Pheochromocytoma resection: current concepts in anesthetic management","volume":"31","author":"Ramakrishna","year":"2015","journal-title":"J. Anaesthesiol. Clin. Pharmacol"},{"key":"R20-43-20260310","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0090-4295(99)00466-5","article-title":"Anesthetic aspects of laparoscopic and open adrenalectomy for pheochromocytoma","volume":"55","author":"Sprung","year":"2000","journal-title":"Urology"},{"key":"R21-43-20260310","first-page":"1118","article-title":"Perianesthetic risks and outcomes of Pheochromocytoma and Paraganglioma resection","volume":"91","author":"Kinney","year":"2000","journal-title":"Anesth. Analg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225007308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261225007308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2025.111544","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T10:05:37Z","timestamp":1773137137000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2025.111544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":21,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2025.111544","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"2025-02-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}