{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T10:32:04Z","timestamp":1783333924703,"version":"3.54.6"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance:<\/jats:title>\n                    <jats:p>Ileosigmoid knotting(ISK), a rare but life-threatening condition which first described in 1845. It occurred when the ileum twisting around the sigmoid colon and causing intestinal obstruction and potential perforation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>A 60-year-old male from the Garbo region of Somali, Ethiopia, presented to the hospital after a a four-day history of intestinal obstruction symptoms. On examination, he was tachycardic and febrile, and exhibited diffuse abdominal tenderness. A diagnosis of intestinal obstruction with generalized peritonitis was made after abdominal x ray. The patient was resuscitated with fluids, started on antibiotics, and a nasogastric tube was placed. Emergency laparotomy revealed ileosigmoid knotting with gangrenous bowel. En bloc resection of the affected ileum and sigmoid colon was performed. An ileo-jejunal anastomosis and an end colostomy were constructed. Despite these interventions, the patient succumbed to uncontrolled sepsis on the fourth postoperative day.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion:<\/jats:title>\n                    <jats:p>Ileosigmoid knotting (ISK), a rare and deadly form of intestinal obstruction, is more common in the \u201cvolvulus belt\u201d regions like Africa and parts of Asia. It involves a twisted knot of the ileum and sigmoid colon and can be caused by factors like a narrow mesentery or hypermobile ileum. ISK is difficult to diagnose with standard tests and often requires surgical exploration. The mortality is high (up to 48 %), especially in resource-limited settings due to various challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Ileosigmoid knotting is a rare and dangerous cause of intestinal obstruction requiring quick action. Poor outcomes are common, especially in resource-limited areas like Ethiopia due to late presentation and limited healthcare resources.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2025.111641","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T20:18:18Z","timestamp":1752610698000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Ileosigmoid knotting: A rare cause of acute abdomen with fatal outcome in a 60-year-old man: Case report from a resource-limited setting"],"prefix":"10.1097","volume":"133","author":[{"given":"Dagne Aschenaki","family":"Argaw","sequence":"first","affiliation":[{"name":"Department of General Surgery, Garbo Primary Hospital, Somali, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wali Ahmed","family":"Nur","sequence":"additional","affiliation":[{"name":"Bachelor Degree Radiology Technology, Masters on Public Health, Chief Executive Officer, Garbo Primary Hospital, Somali, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musse Ahmed","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Somali Regional Health Bureau, Jigjiga, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Ayanle","family":"Hassan","sequence":"additional","affiliation":[{"name":"Master of Public Health, Master of Project Planning and Management and Ph.D Candidate, Somali Regional Health Bureau, Jigjiga, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aidrose Ahmed","family":"Mohamud","sequence":"additional","affiliation":[{"name":"Master of Public Health, Master of Project Planning and Management, Somali Regional Health Bureau, Jigjiga, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Addisu Assfaw","family":"Ayen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Debre Tabor University, Debre Tabor, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"2","key":"R1-132-20260310","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s12262-011-0346-y","article-title":"Ileosigmoid knot","volume":"74","author":"Mandal","year":"2012","journal-title":"Indian J. 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